Point-of-care diagnostics for infectious diseases: From methods to devices

C Wang, M Liu, Z Wang, S Li, Y Deng, N He - Nano Today, 2021 - Elsevier
The current widespread of COVID-19 all over the world, which is caused by SARS-CoV-2
virus, has again emphasized the importance of development of point-of-care (POC) …

LAMP-on-a-chip: Revising microfluidic platforms for loop-mediated DNA amplification

H Zhang, Y Xu, Z Fohlerova, H Chang, C Iliescu… - TrAC Trends in …, 2019 - Elsevier
Nucleic acid amplification for the detection of infectious diseases, food pathogens, or
assessment of genetic disorders require a laboratory setting with specialized equipment and …

SHERLOCK: nucleic acid detection with CRISPR nucleases

MJ Kellner, JG Koob, JS Gootenberg, OO Abudayyeh… - Nature protocols, 2019 - nature.com
Rapid detection of nucleic acids is integral to applications in clinical diagnostics and
biotechnology. We have recently established a CRISPR-based diagnostic platform that …

Rapid PCR powered by microfluidics: A quick review under the background of COVID-19 pandemic

X Dong, L Liu, Y Tu, J Zhang, G Miao, L Zhang… - TrAC Trends in …, 2021 - Elsevier
PCR has been widely used in different fields including molecular biology, pathogen
detection, medical diagnosis, food detection and etc. However, the difficulty of promoting …

The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond

H Zhu, H Zhang, S Ni, M Korabečná, L Yobas… - TrAC Trends in …, 2020 - Elsevier
Infectious diseases, such as the most recent case of coronavirus disease 2019, have
brought the prospect of point-of-care (POC) diagnostic tests into the spotlight. A rapid …

Ultrafast photonic PCR based on photothermal nanomaterials

M You, Z Li, S Feng, B Gao, C Yao, J Hu, F Xu - Trends in biotechnology, 2020 - cell.com
Over the past few decades, PCR has been the gold standard for detecting nucleic acids
(NAs) in various biomedical fields. However, there are several limitations associated with …

Advances in microfluidic PCR for point-of-care infectious disease diagnostics

S Park, Y Zhang, S Lin, TH Wang, S Yang - Biotechnology advances, 2011 - Elsevier
Global burdens from existing or emerging infectious diseases emphasize the need for point-
of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular …

Miniaturized PCR chips for nucleic acid amplification and analysis: latest advances and future trends

C Zhang, D Xing - Nucleic acids research, 2007 - academic.oup.com
The possibility of performing fast and small-volume nucleic acid amplification and analysis
on a single chip has attracted great interest. Devices based on this idea, referred to as micro …

Ultrafast multiplexed detection of SARS-CoV-2 RNA using a rapid droplet digital PCR system

H Yin, Z Wu, N Shi, Y Qi, X Jian, L Zhou, Y Tong… - Biosensors and …, 2021 - Elsevier
We report the first combination of droplet digital and rapid PCR techniques for efficient,
accurate, and quantitative detection of SARS-CoV-2 RNA. The presented rapid digital PCR …

Snakebite envenoming diagnosis and diagnostics

C Knudsen, JA Jürgensen, S Føns, AM Haack… - Frontiers in …, 2021 - frontiersin.org
Snakebite envenoming is predominantly an occupational disease of the rural tropics,
causing death or permanent disability to hundreds of thousands of victims annually. The …