It has been one and a half centuries since Enrico Sertoli published the seminal discovery of
the testicular 'nurse cell', not only a key cell in the testis, but indeed one of the most amazing …

Transcription factor GATA4 is expressed in Sertoli and Leydig cells and is required for
proper development of the murine fetal testis. The role of GATA4 in adult testicular function …

Spermatogenesis is precisely controlled by complex gene expression programs and
involves epigenetic reprogramming, including histone modification and DNA methylation …

This study tested the hypothesis that prepubertal exposure to 4-nonylphenol (NP) affects
reproductive function in male rats. Twenty-four rats at five-weeks-old were randomly divided …

The chemotherapeutic drug cisplatin causes a number of dose-dependent side effects,
including cachexia and testicular damage. Patients receiving a high cumulative dose of …

Sertoli cell morphology has been thoroughly reviewed in the past from basic light and
electron microscopy viewpoints, all of which pointed out the uniqueness of this “mother cell” …

™© ¾‡↕♂♀∠∇±° éÑ PIWI-interacting RNAs (piRNA) are small non-coding RNA
molecules expressed in animal germ cells that interact with PIWI family proteins to form RNA …

Low doses of Bisphenol A (BPA) during development may affect reproduction. In this study,
Fischer 344 rats were exposed to 0.5 or 50 μg BPA/kg bw/day via drinking water from …

We recently investigated mice with Y chromosome gene contribution limited to two, one, or
no Y chromosome genes in respect to their ability to produce haploid round spermatids and …

There is growing interest in using wild animals to monitor the real-life cocktail effect of
environmental chemicals on male reproduction. However, practical difficulties, such as long …