A genome-wide association study reveals susceptibility loci for myocardial infarction/coronary artery disease in Saudi Arabs

SM Wakil, R Ram, NP Muiya, M Mehta, E Andres… - Atherosclerosis, 2016 - Elsevier
Background Multiple loci have been identified for coronary artery disease (CAD) by genome-
wide association studies (GWAS), but no such studies on CAD incidence has been reported …

Polymorphisms in the long non-coding RNA CDKN2B-AS1 may contribute to higher systolic blood pressure levels in hypertensive patients

B Bayoglu, H Yuksel, HA Cakmak, A Dirican… - Clinical …, 2016 - Elsevier
Objectives Hypertension (HT) is a complex disorder influenced by both genetic and
environmental factors. Recent genome-wide association studies have identified a major risk …

[PDF][PDF] Evaluation of association between common genetic variants on chromosome 9p21 and coronary artery disease in Turkish population

HA Çakmak, B Bayoğlu, E Durmaz… - Anatolian Journal of …, 2015 - jag.journalagent.com
Objective: Coronary artery disease (CAD), which develops from complex interactions
between genetic and enviromental factors, is a leading cause of death worldwide. Based on …

Dietary patterns interact with chromosome 9p21 rs1333048 polymorphism on the risk of obesity and cardiovascular risk factors in apparently healthy Tehrani adults

M Mollahosseini, MH Rahimi, MS Yekaninejad… - European journal of …, 2020 - Springer
Purpose Gene-dietary patterns may contribute to determining body composition and related
biochemical indices. The aim of this study was to evaluate interactions between rs1333048 …

Effects of Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ2 gene on metabolic syndrome risk: a meta-analysis

R Zhang, J Wang, R Yang, J Sun, R Chen, H Luo, D Liu… - Gene, 2014 - Elsevier
Background Associations between peroxisome proliferator-activated receptor γ2 (PPARγ2)
gene polymorphism and metabolic syndrome risk remained controversial and ambiguous …

[HTML][HTML] Association of polymorphisms on chromosome 9p21. 3 region with increased susceptibility of abdominal aortic aneurysm in a Chinese Han population

Y Wei, J Xiong, S Zuo, F Chen, D Chen, T Wu… - Journal of Vascular …, 2014 - Elsevier
Objective Several studies have reported that polymorphisms on chromosome 9p21. 3, near
the CDKN2A/2B gene, are strongly associated with increased susceptibility to abdominal …

[HTML][HTML] Association of Genetic Polymorphisms with Abdominal Aortic Aneurysm in the Processes of Apoptosis, Inflammation, and Cholesterol Metabolism

NT Nugroho, M Herten, GF Torsello, N Osada… - Medicina, 2023 - mdpi.com
Background and Objectives: This study aims to identify the minor allele of the single
nucleotide polymorphisms (SNPs) DAB2IP rs7025486, IL6R rs2228145, CDKN2BAS …

The role of CDKN2B in cardiovascular risk in ethnic Saudi Arabs: a validation study

MM AlRasheed, MAM Hefnawy, NN Elsherif… - Gene, 2018 - Elsevier
Background Genome-wide association studies (GWASs) have yielded a wealth of
information furnishing support for the variability in genetic predisposition to disease …

The severity of internal carotid artery stenosis is associated with the cyclin-dependent kinase inhibitor 2A gene expression

B Bayoglu, C Arslan, S Gode, FK Dagistanli… - … of Atherosclerosis and …, 2014 - jstage.jst.go.jp
Aim: The INK4b-ARF-INK4a locus in the chromosome 9p21 region is known to play an
important role in the development of atherosclerosis. The INK4/ARF transcript p16 INK4a …

Genetic risk assessment for cardiovascular disease in Azoreans (Portugal): a general population-based study

M Correia, CC Branco, N Bruffaerts, A Balagué… - Gene, 2013 - Elsevier
The identification of clinically validated genetic variants contributing to complex disorders
raise the possibility to investigate individuals' risk. In this line of research, the present work …