Iran has invariably been under the growing public health threat of cutaneous leishmaniasis
(CL), a significant barrier to local development that hinders the prevention and control efforts …

Leishmaniasis is a neglected and old emerging/reemerging disease that has extremely
increased and expanded in the different geographical areas. Cutaneous leishmaniasis (CL) …

Over the last years, there has been a remarkable increase in the number of unresponsive
patients with anthroponotic cutaneous leishmaniasis (ACL) reported worldwide. The primary …

The ongoing conventional drugs for leishmaniasis treatment are insufficient. The present
study aimed to assess 6-gingerol alone and in combination with amphotericin B on …

Background The control of cutaneous leishmaniasis (CL) is facilitated by knowledge of
factors associated with the treatment failures in endemic countries. The aim of this …

Cutaneous leishmaniasis (CL) is a curable disease; however, due to various risk factors,
unresponsiveness to CL treatments is inevitable. The treatment of CL has been firmly …

Background In recent years, antimonial agents and other synthetic antileishmanial drugs,
such as amphotericin B, paromomycin, and many other drugs, have restrictions in use due to …

Background In the last decade, resistance to antimonials has become a serious problem
due to the emergence of drug-resistant strains. Therefore, understanding the mechanisms …

Background Leishmaniasis is a serious health problem in some parts of the world. In spite of
the many known leishmaniasis control measures, the disease has continued to increase in …

BACKGROUND In addition to the limited therapeutic arsenal and the side effects of
antileishmanial agents, drug resistance hinders disease control. In Brazil, Leishmania …