The Melanoma Antigen Gene (MAGE) protein family is a large, highly conserved group of
proteins that share a common MAGE homology domain. Intriguingly, many MAGE proteins …

Immunotherapy as a treatment for cancer is a growing field of endeavor but reports of
success have been limited for epithelial ovarian cancer. Overcoming the challenges to …

Affinity-optimized T cell receptors can enhance the potency of adoptive T cell therapy.
Afamitresgene autoleucel (afami-cel) is a human leukocyte antigen-restricted autologous T …

Cancer-testis antigens (CTAs) are considered as unique and promising cancer biomarkers
and targets for cancer therapy. CTAs are multifunctional protein group with specific …

Melanoma antigen (MAGE) genes are conserved in all eukaryotes and encode for proteins
sharing a common MAGE homology domain. Although only a single MAGE gene exists in …

Donor spins in silicon are highly competitive qubits for upcoming quantum technologies,
offering complementary metal-oxide semiconductor compatibility, coherence (T 2) times of …

The cancer testis antigen, melanoma-associated antigen A9 (MAGE-A9), is expressed in
many kinds of different human cancers and is an important target for immunotherapy …

Simple Summary Given that selecting an appropriate target is the first step in developing
effective cancer immunotherapy, we focus on melanoma-associated antigens (MAGEs) …

MAGE-A antigens are expressed in a variety of cancers of diverse histological origin and
germinal cells. Due to their relatively high tumor specificity, they represent attractive targets …

ABSTRACT A substantial obstacle to the success of adoptive T cell-based cancer
immunotherapy is the sub-optimal affinity of T-cell receptors (TCRs) for most tumor antigens …