Crosstalk between oxidative and nitrosative stress and arterial stiffness

I Mozos, CT Luca - Current vascular pharmacology, 2017 - ingentaconnect.com
Background: Arterial stiffness, the expression of reduced arterial elasticity, is an effective
predictor of cardiovascular disorders. Oxidative stress is an imbalance between exposure to …

[HTML][HTML] Therapeutic modification of arterial stiffness: An update and comprehensive review

CF Wu, PY Liu, TJ Wu, Y Hung, SP Yang… - World journal of …, 2015 - ncbi.nlm.nih.gov
Arterial stiffness has been recognized as a marker of cardiovascular disease and associated
with long-term worse clinical outcomes in several populations. Age, hypertension, smoking …

Empagliflozin attenuates vascular calcification in mice with chronic kidney disease by regulating the NFR2/HO-1 anti-inflammatory pathway through AMPK activation

CW Lu, CJ Lee, YJ Hsieh, BG Hsu - International Journal of Molecular …, 2023 - mdpi.com
Vascular calcification (VC) is associated with increased cardiovascular risks in patients with
chronic kidney disease (CKD). Sodium-glucose cotransporter 2 inhibitors, such as …

Uric acid and arterial stiffness

A Albu, I Para, M Porojan - Therapeutics and clinical risk …, 2020 - Taylor & Francis
Hyperuricemia is usually associated with hypertension, diabetes mellitus, metabolic
syndrome and chronic kidney disease. Accumulating data from epidemiological studies …

New insights into adiponectin and leptin roles in chronic kidney disease

S Coimbra, S Rocha, MJ Valente, C Catarino… - Biomedicines, 2022 - mdpi.com
Chronic kidney disease (CKD) is commonly associated with a high burden of comorbidities
and poor clinical outcomes. Malnutrition–inflammation–atherosclerosis syndrome is …

Comparison of 24-hour and office pulse wave velocity for prediction of mortality in hemodialysis patients

J Matschkal, CC Mayer, PA Sarafidis… - American journal of …, 2019 - karger.com
Background: Mortality in hemodialysis patients still remains unacceptably high. Enhanced
arterial stiffness is a known cardiovascular risk factor, and pulse wave velocity (PWV) has …

Ambulatory arterial stiffness in chronic kidney disease: a methodological review

A László, G Reusz, J Nemcsik - Hypertension Research, 2016 - nature.com
Cardiovascular mortality is the leading cause of death in chronic kidney disease (CKD) and
end-stage renal disease (ESRD). This can be explained in part by an increased and …

Therapeutic strategy for atherosclerosis based on bone-vascular axis hypothesis

JM Kim, WS Lee, J Kim - Pharmacology & therapeutics, 2020 - Elsevier
As the world's older population grows, the disease burden of atherosclerosis is rapidly
increasing, causing significant morbidity and mortality worldwide. Despite recent …

Sodium nitroprusside stimulation of elastic matrix regeneration by aneurysmal smooth muscle cells

S Bastola, C Kothapalli, A Ramamurthi - Tissue Engineering Part A, 2023 - liebertpub.com
The chronic overexpression of matrix metalloproteases leading to consequent degradation
and loss of the elastic matrix with the reduction in tissue elasticity is central to the …

Impact of the uremic milieu on the osteogenic potential of mesenchymal stem cells

D Lanza, AF Perna, A Oliva, R Vanholder, A Pletinck… - PLoS …, 2015 - journals.plos.org
Human mesenchymal stem cells (hMSCs), the precursors of osteoblasts during
osteogenesis, play a role in the balance of bone formation and resorption, but their …