[HTML][HTML] Normal‑tension glaucoma: Pathogenesis and genetics
A Trivli, I Koliarakis, C Terzidou… - Experimental and …, 2019 - spandidos-publications.com
Normal‑tension glaucoma (NTG) is a multifactorial optic neuropathy which, similar to open‑
angle glaucomas, is characterized by progressive retinal ganglion cell death and …
angle glaucomas, is characterized by progressive retinal ganglion cell death and …
Mendelian genes in primary open angle glaucoma
NC Sears, EA Boese, MA Miller, JH Fingert - Experimental eye research, 2019 - Elsevier
Mutations in each of three genes, myocilin (MYOC), optineurin (OPTN), and TANK binding
kinase 1 (TBK1), may cause primary open-angle glaucoma (POAG) that is inherited as a …
kinase 1 (TBK1), may cause primary open-angle glaucoma (POAG) that is inherited as a …
The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress
MS Shim, A Nettesheim, J Hirt, PB Liton - Autophagy, 2020 - Taylor & Francis
The trabecular meshwork (TM) is a key regulatory tissue of intraocular pressure (IOP) in the
anterior chamber of eye. Dysfunction of the TM causes resistance to outflow of aqueous …
anterior chamber of eye. Dysfunction of the TM causes resistance to outflow of aqueous …
Genomic and transcriptomic characterization of papillary microcarcinomas with lateral neck lymph node metastases
D Perera, R Ghossein, N Camacho… - The Journal of …, 2019 - academic.oup.com
Abstract Context Most papillary microcarcinomas (PMCs) are indolent and subclinical.
However, as many as 10% can present with clinically significant nodal metastases …
However, as many as 10% can present with clinically significant nodal metastases …
[HTML][HTML] Hypertension in African populations: review and computational insights
Hypertension (HTN) is a persistent public health problem affecting approximately 1.3 billion
individuals globally. Treatment-resistant hypertension (TRH) is defined as high blood …
individuals globally. Treatment-resistant hypertension (TRH) is defined as high blood …
[HTML][HTML] Research progress on human genes involved in the pathogenesis of glaucoma
HW Wang, P Sun, Y Chen… - Molecular …, 2018 - spandidos-publications.com
Glaucoma is the leading cause of irreversible blindness globally. It is known that the
incidence of glaucoma is closely associated with inheritance. A large number of studies …
incidence of glaucoma is closely associated with inheritance. A large number of studies …
[HTML][HTML] Biochemical–molecular–genetic biomarkers in the tear film, aqueous humor, and blood of primary open-angle glaucoma patients
MD Pinazo-Durán, V Zanón-Moreno… - Frontiers in …, 2023 - frontiersin.org
Glaucoma is a chronic neurodegenerative disease accounting for the first irreversible cause
of blindness worldwide. Clinical and molecular glaucoma biomarkers indicate the biological …
of blindness worldwide. Clinical and molecular glaucoma biomarkers indicate the biological …
Insights into the regulatory molecules involved in glaucoma pathogenesis
Glaucoma is an important cause of irreversible blindness, characterized by optic nerve
anomalies. Increased intraocular pressure (IOP) and aging are major risk factors. Retinal …
anomalies. Increased intraocular pressure (IOP) and aging are major risk factors. Retinal …
[HTML][HTML] The genetic and endoplasmic reticulum-mediated molecular mechanisms of primary open-angle glaucoma
W Rozpędek-Kamińska, R Wojtczak, JP Szaflik… - International Journal of …, 2020 - mdpi.com
Glaucoma is a heterogenous, chronic, progressive group of eye diseases, which results in
irreversible loss of vision. There are several types of glaucoma, whereas the primary open …
irreversible loss of vision. There are several types of glaucoma, whereas the primary open …
[HTML][HTML] Ibrutinib in gynecological malignancies and breast cancer: a systematic review
JM Metzler, L Burla, D Fink, P Imesch - International journal of molecular …, 2020 - mdpi.com
Ibrutinib is an orally available, small-molecule tyrosine kinase inhibitor. Its main purpose is
to inhibit Bruton's tyrosine kinase (BTK), an enzyme that is crucial in B cell development. It is …
to inhibit Bruton's tyrosine kinase (BTK), an enzyme that is crucial in B cell development. It is …