[HTML][HTML] Impacts of exercise interventions on different diseases and organ functions in mice

S Guo, Y Huang, Y Zhang, H Huang, S Hong… - Journal of sport and health …, 2020 - Elsevier
Background In recent years, much evidence has emerged to indicate that exercise can
benefit people when performed properly. This review summarizes the exercise interventions …

Physical exercise-induced myokines in neurodegenerative diseases

B Lee, M Shin, Y Park, SY Won, KS Cho - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease
(PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are disorders …

Systemic manifestation and contribution of peripheral tissues to Huntington's disease pathogenesis

CL Chuang, F Demontis - Ageing research reviews, 2021 - Elsevier
Huntington disease (HD) is an autosomal dominant neurodegenerative disease that is
caused by expansion of cytosine/adenosine/guanine repeats in the huntingtin (HTT) gene …

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias

A Sujkowski, K Richardson, MV Prifti, RJ Wessells… - Elife, 2022 - elifesciences.org
Endurance exercise is a potent intervention with widespread benefits proven to reduce
disease incidence and impact across species. While endurance exercise supports neural …

Uses for humanised mouse models in precision medicine for neurodegenerative disease

RR Nair, S Corrochano, S Gasco, C Tibbit… - Mammalian …, 2019 - Springer
Neurodegenerative disease encompasses a wide range of disorders afflicting the central
and peripheral nervous systems and is a major unmet biomedical need of our time. There …

Exercise attenuates polyglutamine‐mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy

T Hirunagi, H Nakatsuji, K Sahashi… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Spinal and bulbar muscular atrophy (SBMA) is a hereditary neuromuscular
disorder caused by the expansion of trinucleotide cytosine–adenine–guanine (CAG) …

Effects of lifespan-extending interventions on cognitive healthspan

L Culig, BD Sahbaz, VA Bohr - Expert Reviews in Molecular …, 2023 - cambridge.org
Ageing is known to be the primary risk factor for most neurodegenerative diseases, including
Alzheimer's disease, Parkinson's disease and Huntington's disease. They are currently …

Effects of exercise on skeletal muscle pathophysiology in Huntington's disease

B Trovato, B Magrì, A Castorina, G Maugeri… - Journal of Functional …, 2022 - mdpi.com
Huntington's disease (HD) is a rare, hereditary, and progressive neurodegenerative
disease, characterized by involuntary choreatic movements with cognitive and behavioral …

Longitudinal home-cage automated assessment of climbing behavior shows sexual dimorphism and aging-related decrease in C57BL/6J healthy mice and allows …

RS Bains, H Forrest, RR Sillito, JD Armstrong… - Frontiers in Behavioral …, 2023 - frontiersin.org
Monitoring the activity of mice within their home cage is proving to be a powerful tool for
revealing subtle and early-onset phenotypes in mouse models. Video-tracking, in particular …

Juvenile and adult expression of polyglutamine expanded huntingtin produce distinct aggregate distributions in Drosophila muscle

T Barwell, S Raina, A Page… - Human Molecular …, 2023 - academic.oup.com
While Huntington's disease (HD) is widely recognized as a disease affecting the nervous
system, much evidence has accumulated to suggest peripheral or non-neuronal tissues are …