[HTML][HTML] Pd-, Cu-, and Ni-Catalyzed Reactions: A Comprehensive Review of the Efficient Approaches towards the Synthesis of Antibacterial Molecules

A Zia, S Khalid, N Rasool, N Mohsin, M Imran, SI Toma… - Pharmaceuticals, 2024 - mdpi.com
A strong synthetic tool for many naturally occurring chemicals, polymers, and
pharmaceutical substances is transition metal-catalyzed synthesis. A serious concern to …

Synthesis, in vitro α-glucosidase and α-amylase activities and molecular docking study of oxadiazole-sulphonamide hybrid analogues

H Ullah, MW Aslam, F Rahim, A Hussain… - Chemical Data …, 2023 - Elsevier
Acarbose and voglibose are two different α-glucosidase and α-amylase inhibitors that are
used to manage diabetes mellitus. Sadly, these renowned and therapeutically effective …

Synthesis, in vitro anti-microbial analysis and molecular docking study of aliphatic hydrazide-based benzene sulphonamide derivatives as potent inhibitors of α …

S Khan, S Iqbal, M Shah, W Rehman, R Hussain… - Molecules, 2022 - mdpi.com
A unique series of sulphonamide derivatives was attempted to be synthesized in this study
using a new and effective method. All of the synthesized compounds were verified using …

Quinolone scaffolds as potential drug candidates against infectious microbes: a review

V Sharma, R Das, DK Mehta, D Sharma, S Aman… - Molecular Diversity, 2024 - Springer
Prevalence of microbial infections and new rising pathogens are signified as causative
agent for variety of serious and lethal health crisis in past years. Despite medical advances …

Synthesis, characterization, crystal structure, DFT, HSA, ADMET prediction and antibacterial activity of thiohydantoin analogues

AEMA Allah, W Guerrab, M Maatallah, JT Mague… - Journal of Molecular …, 2024 - Elsevier
In this research, we explore the synthesis and pharmacological evaluation of novel
heterocyclic molecules, drawing inspiration from certain drugs, specifically thiophenytoin. A …

Synthesis and biological evaluation of novel pyrimidine amine derivatives bearing bicyclic monoterpene moieties

M Zhang, Y Wang, S Wang, H Wu - Molecules, 2022 - mdpi.com
A series of novel pinanyl pyrimidine amine derivatives (1e~ 1n) and camphoryl pyrimidine
amine derivatives (2b~ 2f) bearing bicyclic monoterpene moieties were designed and …

3-Allyl-2-(allylthio)-5, 5-diphenyl-3, 5-dihydro-4H-imidazol-4-one: Synthesis, spectroscopic characterization, crystal structure, computational investigations …

AEMA Allah, E Temel, W Guerrab, I Nchioua… - Journal of Molecular …, 2024 - Elsevier
In this investigation, we successfully synthesized a novel thiohydantoin derivative, 3-allyl-2-
(allylthio)-5, 5-diphenyl-3, 5-dihydro-4H-imidazol-4-one (AM 1). The compound underwent …

[HTML][HTML] Synthesis, characterization, DFT, AMDET and molecular docking reveals the binding mechanism of hydroxyl containing bis-Schiff base derivatives: An …

S Arif, S Khan, T Iqbal, BC Yallur, F Rahim… - Results in …, 2024 - Elsevier
One of the major neurodegenerative disorders, Alzheimer's disease (AD) was targeted in the
current study synthesizing bis-Schiff bases derivatives. All the synthesized scaffolds were …

Novel quinolone substituted 1, 3, 4-oxadiazole derivatives: design, synthesis, antimicrobial and anti-inflammatory potential

V Sharma, R Das, DK Mehta, D Sharma - Molecular Diversity, 2024 - Springer
A novel series of quinolone-substituted 1, 3, 4-oxadiazole derivatives 4 (a–l) have been
designed and synthesized. The target compounds were investigated for their antibacterial …

One‐Pot Three‐Component Synthesis of Some 6‐Methoxy‐2‐Naphthyl Pyrimidinones with Molecular Docking and Biological Activities Studies

J Divya, P Gayathri, I Muthuvel, S Suguna… - …, 2024 - Wiley Online Library
A new series of 6‐methoxy‐2‐naphthalene based pyrimidinones were synthesized via one
pot‐three component synthetic reaction of aryl aldehydes, 6‐methoxy‐2‐acetonapthone and …