Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

Mechanistic aspects of the interaction of intercalating metal complexes with nucleic acids

T Biver, F Secco, M Venturini - Coordination Chemistry Reviews, 2008 - Elsevier
Since the discovery of the intercalative binding mode, almost half a century ago, intense
efforts have been devoted to design, synthesize and test new small molecules that can bind …

Nucleic Acid Intercalators and Avidin Probes Derived from Luminescent Cyclometalated Iridium(III)–Dipyridoquinoxaline and –Dipyridophenazine Complexes

KKW Lo, CK Chung, N Zhu - Chemistry–A European Journal, 2006 - Wiley Online Library
Six luminescent cyclometalated iridium (iii)–dipyridoquinoxaline and–dipyridophenazine
complexes [Ir (ppy) 2 (N‐N)](PF6)(Hppy= 2‐phenylpyridine; N‐N= dipyrido [3, 2‐f: 2′, 3 …

Chemical control of the DNA light switch: cycling the switch ON and OFF

Y Liu, A Chouai, NN Degtyareva… - Journal of the …, 2005 - ACS Publications
The emission of the DNA light-switch complex [Ru (bpy) 2 (tpphz)] 2+(bpy= 2, 2 '-bipyridine,
tpphz= tetrapyrido [3, 2-a: 2 ', 3 '-c: 3 '', 2 ''-h: 2 ''', 3 '''-j] phenazine) can be reversibly turned …

New tailored substituted benzothiazole Schiff base Cu (II)/Zn (II) antitumor drug entities: effect of substituents on DNA binding profile, antimicrobial and cytotoxic …

S Zehra, M Shavez Khan, I Ahmad… - Journal of Biomolecular …, 2019 - Taylor & Francis
New tailored Cu (II) & Zn (II) metal-based antitumor drug entities were synthesized from
substituted benzothiazole o‒vanillin Schiff base ligands. The complexes were thoroughly …

Photophysical Properties of [Ru(phen)2(dppz)]2+ Intercalated into DNA:  An Integrated Car−Parrinello and TDDFT Study

S Fantacci, F De Angelis, A Sgamellotti… - Journal of the …, 2005 - ACS Publications
Combined Car− Parrinello and time-dependent DFT calculations performed on [Ru (phen)
2dppz] 2+ intercalated into an adenine− thymine tetramer reveal a remarkable influence of …

Ruthenium (II) Complex of Hbopip: Synthesis, Characterization, pH-Induced Luminescence “Off− On− Off” Switch, and Avid Binding to DNA

MJ Han, LH Gao, YY Lü, KZ Wang - The Journal of Physical …, 2006 - ACS Publications
A novel ruthenium (II) complex of [Ru (bpy) 2 (Hbopip)](ClO4) 2 (in which bpy= 2, 2 '-
bipyridine, Hbopip= 2-(4-benzoxazolyl) phenylimidazo [4, 5-f][1, 10] phenanthroline) was …

A theoretical study of Ru (II) polypyridyl DNA intercalators: structure and electronic absorption spectroscopy of [Ru (phen) 2 (dppz)] 2+ and [Ru (tap) 2 (dppz)] 2+ …

D Ambrosek, PF Loos, X Assfeld, C Daniel - Journal of inorganic …, 2010 - Elsevier
The structural and spectroscopic properties of [Ru (phen) 2 (dppz)] 2+ and [Ru (tap) 2
(dppz)] 2+(phen= 1, 10-phenanthroline; tap= 1, 4, 5, 8-tetraazaphenanthrene; dppz …

Synthesis, characterization and DNA-binding properties of rac-[Ru (5, 6-dmp) 2 (dppz)] 2+–Enantiopreferential DNA binding and co-ligand promoted exciton coupling

PU Maheswari, V Rajendiran, M Palaniandavar… - Journal of inorganic …, 2006 - Elsevier
The new mixed ligand complex [Ru (5, 6-dmp) 2 (dppz)] Cl2 [5, 6-dmp= 5, 6-dimethyl-1, 10-
phenanthroline, dppz= dipyrido [3, 2-a: 2′, 3′-c] phenazine] has been isolated and its …

Lifetime heterogeneity of DNA-bound dppz complexes originates from distinct intercalation geometries determined by complex–complex interactions

J Andersson, LH Fornander, M Abrahamsson… - Inorganic …, 2013 - ACS Publications
Despite the extensive interest in structurally explaining the photophysics of DNA-bound [Ru
(phen) 2dppz] 2+ and [Ru (bpy) 2dppz] 2+, the origin of the two distinct emission lifetimes of …