Chemistry and applications of functionalized 2, 4‐thiazolidinediones

AM Ibrahim, ME Shoman… - European Journal of …, 2023 - Wiley Online Library
Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …

Synthetic Strategies of Thiazolidine-2, 4-dione Derivatives for the Development of New Anti-diabetic Agents: Compressive Review

PK Ray, K Shabana, Salahuddin… - Current Topics in …, 2024 - benthamdirect.com
Background: Thiazolidine-2, 4-dione (2, 4-TZD) is a flexible pharmacophore and a
privileged platform and contains a five-membered ring with a 2-oxygen atom with double …

Thiazolidine derivatives: In vitro toxicity assessment against promastigote and amastigote forms of Leishmania infantum and ultrastructural study

ALA Gouveia, FAB Santos, LC Alves… - Experimental …, 2022 - Elsevier
Neglected diseases, such as Leishmaniasis, constitute a group of communicable diseases
that occur mainly in tropical countries. Considered a public health problem with limited …

Synthesis and anti-HIV activities of phorbol derivatives

X Huang, T Chengrun, X Huang, Y Yun, LI Qirun… - Chinese Journal of …, 2024 - Elsevier
In this study, 37 derivatives of phorbol esters were synthesized and their anti-HIV-1 activities
evaluated, building upon our previous synthesis of 51 phorbol derivatives. 12-Para-electron …

Functionalized Morpholine-thiazole Scaffold: Synthetic Strategies and Applications

TE Ali, MA Assiri, MN Alqahtani - Current Organic Synthesis, 2024 - benthamdirect.com
The thiazole derivatives as important members of heterocyclic compounds have attracted
much synthetic interest due to their different biological properties. In recent years, studies on …

[PDF][PDF] Synthesis and Hypoglycemic Activity of the Derivatives of 4-(1, 3-Thiazolidine-5-Ylidene) Pyrazole-3-Carbonic Acid and its Esters

M Bratenko, O Perepelytsya… - Biointerface …, 2021 - biointerfaceresearch.com
A preparatively convenient method for synthesizing a series of new (pyrazole-4-yl)
methylenethiazolidine structures fictionalized by the carboxylate or carboxylic group in the …

[PDF][PDF] Synthesis and Antimicrobial Activity of 2-amino-4-pyrazolyl-4Н-1, 3-oxazines

N Panasenko, M Bratenko, N Voytkevich, A Antoniv… - 2024 - nanobioletters.com
The article is devoted to synthesizing and investigating the antimicrobial action of a class of
functionalized heterocyclic systems. 2-amino-4-pyrazolyl-4H-1, 3-oxazines were obtained by …

[引用][C] Experimental and theoretical approach to cysteine-based perfluorinated derivatives as non-cleavage linkers for bioconjugation

C Gualán, S Pakary - 2022 - Universidad de Investigación de …