Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films
E Parra, J Pérez-Gil - Chemistry and physics of lipids, 2015 - Elsevier
The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …
membrane-based system composed of multiple lipids and specific proteins, the primary …
Respiratory fluid mechanics and transport processes
JB Grotberg - Annual review of biomedical engineering, 2001 - annualreviews.org
▪ Abstract The field of respiratory flow and transport has experienced significant research
activity over the past several years. Important contributions to the knowledge base come …
activity over the past several years. Important contributions to the knowledge base come …
Computational lung modelling in respiratory medicine
Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …
[图书][B] Interfacial convection in multilayer systems
A Nepomnyashchy, JC Legros, I Simanovskii - 2006 - Springer
The interfacial convection in multilayer systems is a widespread phenomenon that is of great
importance in numerous branches of technology, including chemical engineering, space …
importance in numerous branches of technology, including chemical engineering, space …
The POOR Get POORer: a hypothesis for the pathogenesis of ventilator-induced lung injury
DP Gaver III, GF Nieman, LA Gatto… - American journal of …, 2020 - atsjournals.org
Protective ventilation strategies for the injured lung currently revolve around the use of low
Vt, ostensibly to avoid volutrauma, together with positive end-expiratory pressure to increase …
Vt, ostensibly to avoid volutrauma, together with positive end-expiratory pressure to increase …
[HTML][HTML] Effects of lung surfactant proteins, SP-B and SP-C, and palmitic acid on monolayer stability
J Ding, DY Takamoto, A Von Nahmen, MM Lipp… - Biophysical journal, 2001 - cell.com
Langmuir isotherms and fluorescence and atomic force microscopy images of synthetic
model lung surfactants were used to determine the influence of palmitic acid and synthetic …
model lung surfactants were used to determine the influence of palmitic acid and synthetic …
Pressure gradient, not exposure duration, determines the extent of epithelial cell damage in a model of pulmonary airway reopening
SS Kay, AM Bilek, KC Dee… - Journal of Applied …, 2004 - journals.physiology.org
The reduction of tidal volume during mechanical ventilation has been shown to reduce
mortality of patients with acute respiratory distress syndrome, but epithelial cell injury can …
mortality of patients with acute respiratory distress syndrome, but epithelial cell injury can …
The biophysical function of pulmonary surfactant
S Rugonyi, SC Biswas, SB Hall - Respiratory physiology & neurobiology, 2008 - Elsevier
Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two
key aspects of this function: that the surfactant film forms rapidly; and that when compressed …
key aspects of this function: that the surfactant film forms rapidly; and that when compressed …
Biomechanics of liquid–epithelium interactions in pulmonary airways
SN Ghadiali, DP Gaver - Respiratory physiology & neurobiology, 2008 - Elsevier
The delicate structure of the lung epithelium makes it susceptible to surface tension induced
injury. For example, the cyclic reopening of collapsed and/or fluid-filled airways during the …
injury. For example, the cyclic reopening of collapsed and/or fluid-filled airways during the …
The steady propagation of a surfactant-laden liquid plug in a two-dimensional channel
H Fujioka, JB Grotberg - Physics of Fluids, 2005 - pubs.aip.org
In this study, we investigate the steady propagation of a liquid plug in a two-dimensional
channel lined by a uniform, thin liquid film. The liquid contains soluble surfactant that can …
channel lined by a uniform, thin liquid film. The liquid contains soluble surfactant that can …