On the integration of space, time, and memory

H Eichenbaum - Neuron, 2017 - cell.com
The hippocampus is famous for mapping locations in spatially organized environments, and
several recent studies have shown that hippocampal networks also map moments in …

Memory as perception of the past: compressed time inMind and brain

MW Howard - Trends in cognitive sciences, 2018 - cell.com
In the visual system retinal space is compressed such that acuity decreases further from the
fovea. Different forms of memory may rely on a compressed representation of time …

The same hippocampal CA1 population simultaneously codes temporal information over multiple timescales

W Mau, DW Sullivan, NR Kinsky, ME Hasselmo… - Current Biology, 2018 - cell.com
It has long been hypothesized that a primary function of the hippocampus is to discover and
exploit temporal relationships between events. Previously, it has been reported that …

[HTML][HTML] Fronto-parietal cortical circuits encode accumulated evidence with a diversity of timescales

BB Scott, CM Constantinople, A Akrami, TD Hanks… - Neuron, 2017 - cell.com
Decision-making in dynamic environments often involves accumulation of evidence, in
which new information is used to update beliefs and select future actions. Using in vivo …

A temporal record of the past with a spectrum of time constants in the monkey entorhinal cortex

IM Bright, MLR Meister, NA Cruzado… - Proceedings of the …, 2020 - National Acad Sciences
Episodic memory is believed to be intimately related to our experience of the passage of
time. Indeed, neurons in the hippocampus and other brain regions critical to episodic …

Internally generated time in the rodent hippocampus is logarithmically compressed

R Cao, JH Bladon, SJ Charczynski, ME Hasselmo… - Elife, 2022 - elifesciences.org
Abstract The Weber-Fechner law proposes that our perceived sensory input increases with
physical input on a logarithmic scale. Hippocampal 'time cells' carry a record of recent …

Sequential firing codes for time in rodent medial prefrontal cortex

Z Tiganj, MW Jung, J Kim, MW Howard - Cerebral Cortex, 2017 - academic.oup.com
A subset of hippocampal neurons, known as “time cells” fire sequentially for circumscribed
periods of time within a delay interval. We investigated whether medial prefrontal cortex …

Conjunctive representation of what and when in monkey hippocampus and lateral prefrontal cortex during an associative memory task

NA Cruzado, Z Tiganj, SL Brincat, EK Miller… - …, 2020 - Wiley Online Library
Adaptive memory requires the organism to form associations that bridge between events
separated in time. Many studies show interactions between hippocampus (HPC) and …

Compressed timeline of recent experience in monkey lateral prefrontal cortex

Z Tiganj, JA Cromer, JE Roy, EK Miller… - Journal of cognitive …, 2018 - direct.mit.edu
Cognitive theories suggest that working memory maintains not only the identity of recently
presented stimuli but also a sense of the elapsed time since the stimuli were presented …

Navigating through time: a spatial navigation perspective on how the brain may encode time

JB Issa, G Tocker, ME Hasselmo… - Annual Review of …, 2020 - annualreviews.org
Interval timing, which operates on timescales of seconds to minutes, is distributed across
multiple brain regions and may use distinct circuit mechanisms as compared to millisecond …