An update on retinal prostheses

LN Ayton, N Barnes, G Dagnelie, T Fujikado… - Clinical …, 2020 - Elsevier
Retinal prostheses are designed to restore a basic sense of sight to people with profound
vision loss. They require a relatively intact posterior visual pathway (optic nerve, lateral …

Retinal stimulation strategies to restore vision: Fundamentals and systems

L Yue, JD Weiland, B Roska, MS Humayun - Progress in retinal and eye …, 2016 - Elsevier
Retinal degeneration, a leading cause of blindness worldwide, is primarily characterized by
the dysfunctional/degenerated photoreceptors that impair the ability of the retina to detect …

Random noise stimulation improves neuroplasticity in perceptual learning

A Fertonani, C Pirulli, C Miniussi - Journal of Neuroscience, 2011 - Soc Neuroscience
Perceptual learning is considered a manifestation of neural plasticity in the human brain. We
investigated brain plasticity mechanisms in a learning task using noninvasive transcranial …

Retinal prosthesis

JD Weiland, MS Humayun - IEEE Transactions on Biomedical …, 2014 - ieeexplore.ieee.org
Retinal prosthesis has been translated from the laboratory to the clinic over the past two
decades. Currently, two devices have regulatory approval for the treatment of retinitis …

A model of ganglion axon pathways accounts for percepts elicited by retinal implants

M Beyeler, D Nanduri, JD Weiland, A Rokem… - Scientific reports, 2019 - nature.com
Degenerative retinal diseases such as retinitis pigmentosa and macular degeneration cause
irreversible vision loss in more than 10 million people worldwide. Retinal prostheses, now …

Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration

AC Weitz, D Nanduri, MR Behrend… - Science translational …, 2015 - science.org
Retinal prosthetic implants are the only approved treatment for retinitis pigmentosa, a
disease of the eye that causes blindness through gradual degeneration of photoreceptors …

Conductive hydrogels: mechanically robust hybrids for use as biomaterials

RA Green, RT Hassarati, JA Goding… - Macromolecular …, 2012 - Wiley Online Library
A hybrid system for producing conducting polymers within a doping hydrogel mesh is
presented. These conductive hydrogels demonstrate comparable electroactivity to …

[HTML][HTML] Therapy with voretigene neparvovec. How to measure success?

K Stingl, M Kempf, R Jung, F Kortuem, G Righetti… - Progress in Retinal and …, 2023 - Elsevier
Retinal gene supplementation therapy such as the first approved one, voretigene
neparvovec, delivers a functioning copy of the missing gene enabling the protein …

Microscopic magnetic stimulation of neural tissue

G Bonmassar, SW Lee, DK Freeman, M Polasek… - Nature …, 2012 - nature.com
Electrical stimulation is currently used to treat a wide range of cardiovascular, sensory and
neurological diseases. Despite its success, there are significant limitations to its application …

Selectivity of direct and network-mediated stimulation of the retinal ganglion cells with epi-, sub-and intraretinal electrodes

D Boinagrov, S Pangratz-Fuehrer… - Journal of neural …, 2014 - iopscience.iop.org
Objective. Intra-retinal placement of stimulating electrodes can provide close and stable
proximity to target neurons. We assessed improvement in stimulation thresholds and …