Intracellular signaling mechanisms that shape postsynaptic GABAergic synapses

H Jung, S Kim, J Ko, JW Um - Current Opinion in Neurobiology, 2023 - Elsevier
Postsynaptic GABAergic receptors interact with various membrane and intracellular proteins
to mediate inhibitory synaptic transmission. They form structural and/or signaling synaptic …

Regulation of NLGN3 and the synaptic Rho-GEF signaling pathway by CDK5

J Jeong, W Han, E Hong, S Pandey, Y Li… - Journal of …, 2023 - Soc Neuroscience
Neuroligins (NLGNs) are postsynaptic cell adhesion molecules that are involved in synapse
assembly and function. The NLGN gene family consists of 5 genes (NLGN1-3, 4X, and 4Y) …

Upregulation of Spinal MDGA1 in Rats After Nerve Injury Alters Interactions Between Neuroligin-2 and Postsynaptic Scaffolding Proteins and Increases GluR1 Subunit …

HL Li, RJ Guo, ZR Ai, S Han, Y Guan, JF Li… - Neurochemical …, 2024 - Springer
Previous studies suggested that postsynaptic neuroligin-2 may shift from inhibitory toward
excitatory function under pathological pain conditions. We hypothesize that nerve injury may …

GABAA receptors and neuroligin 2 synergize to promote synaptic adhesion and inhibitory synaptogenesis

Y Sui, M Mortensen, B Yuan, MW Nicholson… - Frontiers in Cellular …, 2024 - frontiersin.org
GABAA receptors (γ-aminobutyric acid-gated receptors type A; GABAARs), the major
structural and functional postsynaptic components of inhibitory synapses in the mammalian …

N-Linked Glycosylation Is Fundamentally Linked to the Surface Expression of Neuroligins

TP Cast - 2023 - search.proquest.com
N-linked glycosylation is one of the most prevalent forms of post-translational modification,
decorating secreted and cell-surface transmembrane proteins as they are trafficked along …

Reduced Volumetric Volatility and Decreased Inhibitory Stabilization of Dendritic Spines in the Aging Primary Somatosensory Cortex

AL Ducote - 2023 - search.proquest.com
Though formation and long-term maintenance of memories may seem to go hand in hand,
these two processes require opposing properties of synaptic plasticity and stability that must …

Control de la Conductancia del Receptor GABAA por Residuos Intracelulares: Implicancias en la Regulación del Canal por Fosforilación.

DE Fraig Lobos - 2023 - repositorio.udec.cl
Los receptores de ácido-aminobutírico tipo A (GABAARs) son los principales
responsables de la neurotransmisión inhibitoria en el sistema nervioso central (SNC) en …