Fluctuations in the neuronal calcium concentration,[Ca2÷], act as signals which are
enormously important for a variety of reasons. Ca 2+ acts as the major trigger for …

Chromaffin cells (CCs) of the adrenal gland and the sympathetic nervous system produce
the catecholamines (epinephrine and norepinephrine; EPI and NE) needed to coordinate …

Experimental observations indicate that Ca 2+-induced Ca 2+ release (CICR) may underlie
Ca 2+ oscillations in a variety of cells. In its original version, a theoretical model for signal …

Intense stimuli, such as trains of depolarizing pulses or the caffeine-induced release of
calcium from intracellular stores, readily depress the secretory response in neuroendocrine …

Glutamate toxicity on PC12 cells is mediated by oxidative stress as a consequence of the
inhibition of a cystine uptake system with depletion of GSH. In this study we report that …

Recent experiments on a variety of neuroendocrine cells indicate that intense stimuli readily
depress the secretory response. The most likely explanation for this depression is that a pool …

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The presence and physiological role of Ca2+-induced Ca2+ release (CICR) in nonmuscle
excitable cells has been investigated only indirectly through measurements of cytosolic …

5. I. 2. Ruthenium Red 5.1. 3. Procaine 5.1. 4. Dantrolene 5.1 S. Sulfhydryl reagents 5.1. 6.
Neurotoxins 5.1. 7. Cardiac glycosides 5.1. 8. Doxorubicin 5.2. Endogenous modulators of …

Intracellular Ca2+ oscillations are commonly observed in a large number of cell types in
response to stimulation by an extracellular agonist. In most cell types the mechanism of …