[HTML][HTML] The diagnosis of limbal stem cell deficiency
Q Le, J Xu, SX Deng - The ocular surface, 2018 - Elsevier
Limbal stem cells (LSCs) maintain the normal homeostasis and wound healing of corneal
epithelium. Limbal stem cell deficiency (LSCD) is a pathologic condition that results from the …
epithelium. Limbal stem cell deficiency (LSCD) is a pathologic condition that results from the …
[HTML][HTML] Stem cell niche microenvironment
The cornea comprises a pool of self-regenerating epithelial cells that are crucial to
preserving clarity and visibility. Limbal epithelial stem cells (LESCs), which live in a …
preserving clarity and visibility. Limbal epithelial stem cells (LESCs), which live in a …
[HTML][HTML] Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation
Whilst demonstrated extensively in vitro, the control of cell behaviour via modulation of
substrate compliance in live tissues has not been accomplished to date. Here we propose …
substrate compliance in live tissues has not been accomplished to date. Here we propose …
[HTML][HTML] Three-dimensional structure of the mammalian limbal stem cell niche
Although the existence of the limbal stem cell (LSC) niche is accepted, precise knowledge of
its three-dimensional (3D) architecture remains incomplete. The LSC niche was explored on …
its three-dimensional (3D) architecture remains incomplete. The LSC niche was explored on …
[HTML][HTML] In vivo morphology of the limbal palisades of vogt correlates with progressive stem cell deficiency in aniridia-related keratopathy
N Lagali, U Edén, TP Utheim, X Chen… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: To investigate morphologic alterations in the limbal palisades of Vogt in a
progressive form of limbal stem cell deficiency. Methods.: Twenty Norwegian subjects (40 …
progressive form of limbal stem cell deficiency. Methods.: Twenty Norwegian subjects (40 …
[HTML][HTML] Age-related changes in human corneal epithelial thickness measured with anterior segment optical coherence tomography
Purpose.: To measure corneal and limbal epithelial thickness (ET) in normal subjects and to
evaluate its variation with age by using anterior segment optical coherence tomography (AS …
evaluate its variation with age by using anterior segment optical coherence tomography (AS …
[HTML][HTML] Rapid tissue engineering of biomimetic human corneal limbal crypts with 3D niche architecture
Limbal epithelial stem cells are responsible for the maintenance of the human corneal
epithelium and these cells reside in a specialised stem cell niche. They are located at the …
epithelium and these cells reside in a specialised stem cell niche. They are located at the …
A review on digital image processing techniques for in-vivo confocal images of the cornea
This work reviews the scientific literature regarding digital image processing for in vivo
confocal microscopy images of the cornea. We present and discuss a selection of prominent …
confocal microscopy images of the cornea. We present and discuss a selection of prominent …
[HTML][HTML] Limbal basal cell density decreases in limbal stem cell deficiency
EH Chan, L Chen, JY Rao, F Yu, SX Deng - American journal of …, 2015 - Elsevier
Purpose To investigate changes in limbal basal epithelial cell density in eyes with limbal
stem cell deficiency (LSCD) using in vivo confocal laser scanning microscopy. Design …
stem cell deficiency (LSCD) using in vivo confocal laser scanning microscopy. Design …
[HTML][HTML] Early phenotypic features of aniridia-associated keratopathy and association with PAX6 coding mutations
Purpose To investigate corneal phenotype in aniridia-associated keratopathy (AAK)
including its earliest manifestations, in relation to PAX6 mutational status. Methods 46 …
including its earliest manifestations, in relation to PAX6 mutational status. Methods 46 …