Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Cannabis, cannabinoids, and sleep: a review of the literature

KA Babson, J Sottile, D Morabito - Current psychiatry reports, 2017 - Springer
Cannabis, Cannabinoids, and Sleep: a Review of the Literature | Current Psychiatry Reports
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Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems

J Moltke, C Hindocha - Journal of cannabis research, 2021 - Springer
Background Public and medical interest in cannabidiol (CBD) has been rising, and CBD is
now available from various sources. Research into the effects of low-dose CBD on outcomes …

Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age

JA Crippa, FS Guimarães, AC Campos… - Frontiers in …, 2018 - frontiersin.org
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Cannabis, cannabinoids, and health

G Lafaye, L Karila, L Blecha… - Dialogues in clinical …, 2017 - Taylor & Francis
Cannabis (also known as marijuana) is the most frequently used illicit psychoactive
substance in the world. Though it was long considered to be a “soft” drug, studies have …

Effects of cannabidiol in the treatment of patients with Parkinson's disease: an exploratory double-blind trial

MHN Chagas, AW Zuardi, V Tumas… - Journal of …, 2014 - journals.sagepub.com
Introduction: Parkinson's disease (PD) has a progressive course and is characterized by the
degeneration of dopaminergic neurons. Although no neuroprotective treatments for PD have …

[HTML][HTML] Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

IM Linares, AW Zuardi, LC Pereira… - Brazilian Journal of …, 2018 - SciELO Brasil
Objective: Cannabidiol (CBD), one of the non-psychotomimetic compounds of Cannabis
sativa, causes anxiolytic-like effects in animals, with typical bell-shaped dose-response …

[HTML][HTML] Effects of cannabinoids on sleep and their therapeutic potential for sleep disorders

M Kaul, PC Zee, AS Sahni - Neurotherapeutics, 2021 - Elsevier
The recent trend for legalization of medicinal cannabis and cannabinoid-containing
products, together with their soporific effects, has led to a surge of interest of their potential …

[PDF][PDF] Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a …

MHN Chagas, AL Eckeli, AW Zuardi… - Journal of Clinical …, 2014 - med.upenn.edu
What is known and objective: Cannabidiol (CBD) is the main non-psychotropic component
of the Cannabis sativa plant. REM sleep behaviour disorder (RBD) is a parasomnia …