Bioactivity of natural polyphenols as antiparasitic agents and their biochemical targets
J Soto-Sánchez - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Background: Leishmaniasis and trypanosomiasis are diseases that affect public health
worldwide due to their high incidence, morbidity, and mortality. Available treatments are …
worldwide due to their high incidence, morbidity, and mortality. Available treatments are …
Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer's Disease
Alzheimer's disease (AD) has been associated with the hallmark features of cholinergic
dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic transmission, which …
dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic transmission, which …
Evaluation of Antimalarial Activity of Ethanolic Extract of Annona muricata L.: An in vivo and an in silico Approach
CO Nwonuma, EA Balogun… - Journal of Evidence …, 2023 - journals.sagepub.com
In Nigeria, Annona muricata L. has been used to treat a variety of ailments. The mechanism
of the antimalarial activity of ethanolic leaf extract of Annona muricata (EEAML) was …
of the antimalarial activity of ethanolic leaf extract of Annona muricata (EEAML) was …
A systematic review on ethnobotany, phytochemistry and pharmacology of Dioscorea bulbifera L.(Dioscoreaceae)
S Sharma, S Kaul, MK Dhar - South African Journal of Botany, 2024 - Elsevier
Dioscorea bulbifera L.(Dioscoreaceae) is extensively being used in African, Chinese and
Indian traditional medicinal systems since ages. It is an ingredient in many herbal and …
Indian traditional medicinal systems since ages. It is an ingredient in many herbal and …
An Allosteric Inhibitory Potential of Triterpenes from Combretum racemosum on the Structural and Functional Dynamics of Plasmodium falciparum Lactate …
Multidrug resistance is a significant drawback in malaria treatment, and mutations in the
active sites of the many critical antimalarial drug targets have remained challenging …
active sites of the many critical antimalarial drug targets have remained challenging …
Antimalarial potential of compounds isolated from Mammea siamensis T. Anders. flowers: in vitro and molecular docking studies
Background: The emergence of antimalarial drug resistance encourages the search for new
antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a …
antimalarial agents. Mammea siamensis belongs to the Calophyllaceae family, which is a …
In Silico Studies of Four Compounds of Cecropia obtusifolia against Malaria Parasite
CA Lobato-Tapia, Y Moreno-Hernández… - Molecules, 2023 - mdpi.com
Malaria is a disease that affects many people in the world. In Mexico, malaria remains an
active disease in certain regions, particularly in the states of Chiapas and Chihuahua. While …
active disease in certain regions, particularly in the states of Chiapas and Chihuahua. While …
Antiplasmodial potential of isolated xanthones from Mesua ferrea Linn. roots: an in vitro and in silico molecular docking and pharmacokinetics study
Background Malaria is a major global health concern, particularly in tropical and subtropical
countries. With growing resistance to first-line treatment with artemisinin, there is an urgent …
countries. With growing resistance to first-line treatment with artemisinin, there is an urgent …
30-norfriedelanes and other compounds from the stem bark and fruits of Caloncoba glauca (Achariaceae), their antiplasmodial activity, structure-activity relationship …
Two new 30-norfriedelane triterpenoids namely glaucalactone C (1) and glaucanoic acid (2)
along with sixteen known compounds (3–18) have been isolated from the methanolic …
along with sixteen known compounds (3–18) have been isolated from the methanolic …
Structure-based virtual screening against multiple Plasmodium falciparum kinases reveals antimalarial compounds
The continuous emergence of resistance against most frontline antimalarial drugs has led to
countless deaths in malaria-endemic countries, counting 619,000 deaths in 2021, with …
countless deaths in malaria-endemic countries, counting 619,000 deaths in 2021, with …