Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

The homeostasis of the central nervous system (CNS) is ensured by the endothelial,
epithelial, mesothelial and glial brain barriers, which strictly control the passage of …

Tight junctions (TJs) are composed of a claudin-based anastomosing network of TJ strands
at which plasma membranes of adjacent epithelial cells are closely attached to regulate the …

Epithelial and endothelial monolayers are multicellular sheets that form barriers between the
'outside'and 'inside'of tissues. Cell-cell junctions, made by adherens junctions, tight junctions …

INTRODUCTION The ability to sense and respond to mechanical force is an intrinsic
property of cells that is critical for normal cell function and often deregulated in disease …

The epithelial cell tight junction structure is the site of the transepithelial movement of solutes
and water between epithelial cells (paracellular permeability). Paracellular permeability can …

Adherens junctions are tensile structures that couple epithelial cells together. Junctional
tension can arise from cell-intrinsic application of contractility or from the cell-extrinsic forces …

The functional and structural concept of tight junctions has developed after discovery of
claudin and TAMP proteins. Many of these proteins contribute to epi-and endothelial barrier …

During embryonic development, regeneration, and homeostasis, cells have to migrate and
physically integrate into the target tissues where they ultimately execute their function. While …

INTRODUCTION How biological properties scale with organ or body size is a question
fundamental to development and physiology; however, at the cellular level, the scaling …