Spondyloarthritis (SpA) refers to a group of diseases with inflammation in joints and spines.
In this family, ankylosing spondylitis (AS) is a rare but classic form that mainly involves the …

The continuous recirculation of naive T cells and their subsequent migration to tissue
following activation is crucial for maintaining protective immunity against invading …

To achieve longevity, IgA plasma cells require a sophisticated anatomical microenvironment
that provides cytokines, cell-cell contacts, and nutrients as well as metabolites. The intestinal …

Aberrant glycosylation resulting from altered expression of sialyltransferases, such as ST3 β-
galactoside α2-3-sialyltransferase 6, plays an important role in disease progression in …

Spleen dysfunction is central to morbidity and mortality in children with sickle cell anemia
(SCA). The initiation and determinants of spleen injury, including acute splenic …

Deciphering the mechanisms of hematopoietic stem/progenitor cell (HSPC) mobilization and
homing is important for the development of strategies to enhance the efficacy of HSPC …

Aberrant glycosylation modulates different aspects of tumor biology, and it has long been
recognized as a hallmark of cancer. Among the different forms of glycosylation, sialylation …

α4β7 integrin is a cell adhesion receptor that is crucial for the migration of hematopoietic
progenitors and mature effector cells in the periphery, but its role in adult hematopoiesis is …

The hematopoietic inductive microenvironment (HIM) is where hematopoietic
stem/progenitor cells grow and develop. Hematopoietic stromal cells were the key …

We previously studied the role of β1 integrin and some of its different α partners relevant to
erythropoiesis. Although clear and consistent answers regarding the role of α4β1 (VLA-4) …