Follicular lymphoma

A Carbone, S Roulland, A Gloghini, A Younes… - Nature reviews Disease …, 2019 - nature.com
Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

From genetics to the clinic: a translational perspective on follicular lymphoma

S Huet, P Sujobert, G Salles - Nature Reviews Cancer, 2018 - nature.com
Follicular lymphoma (FL) is the most frequent indolent B cell lymphoma and is still
considered to be incurable. In recent years, whole-exome sequencing studies of large …

Axicabtagene ciloleucel in relapsed or refractory indolent non-Hodgkin lymphoma (ZUMA-5): a single-arm, multicentre, phase 2 trial

CA Jacobson, JC Chavez, AR Sehgal… - The lancet …, 2022 - thelancet.com
Background Most patients with advanced-stage indolent non-Hodgkin lymphoma have
multiple relapses. We assessed axicabtagene ciloleucel autologous anti-CD19 chimeric …

NCCN guidelines® insights: B-cell lymphomas, version 5.2021: featured updates to the NCCN guidelines

AD Zelenetz, LI Gordon, JE Chang, B Christian… - Journal of the National …, 2021 - jnccn.org
In the last decade, a better understanding of the molecular pathogenesis of B-cell non-
Hodgkin lymphomas has resulted in the development of novel targeted therapies, such as …

Follicular lymphoma in the modern era: survival, treatment outcomes, and identification of high-risk subgroups

CL Batlevi, F Sha, A Alperovich, A Ni, K Smith… - Blood cancer …, 2020 - nature.com
Patients with follicular lymphoma (FL) frequently require multiple treatments during their
disease course; however, survival based on lines of treatment remains poorly described in …

Validation of POD24 as a robust early clinical end point of poor survival in FL from 5225 patients on 13 clinical trials

C Casulo, JG Dixon, J Le-Rademacher… - Blood, The Journal …, 2022 - ashpublications.org
Observational studies and stand-alone trials indicate that patients with follicular lymphoma
(FL) who experience disease progression within 24 months of front-line …

Cause of death in follicular lymphoma in the first decade of the rituximab era: a pooled analysis of French and US cohorts

C Sarkozy, MJ Maurer, BK Link… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Although the life expectancy of patients with follicular lymphoma (FL) has
increased, little is known of their causes of death (CODs) in the rituximab era. Patients and …

A simplified scoring system in de novo follicular lymphoma treated initially with immunochemotherapy

E Bachy, MJ Maurer, TM Habermann… - Blood, The Journal …, 2018 - ashpublications.org
In follicular lymphoma (FL), no prognostic index has been built based solely on a cohort of
patients treated with initial immunochemotherapy. There is currently a need to define …

A gene-expression profiling score for prediction of outcome in patients with follicular lymphoma: a retrospective training and validation analysis in three international …

S Huet, B Tesson, JP Jais, AL Feldman… - The Lancet …, 2018 - thelancet.com
Background Patients with follicular lymphoma have heterogeneous outcomes. Predictor
models to distinguish, at diagnosis, between patients at high and low risk of progression are …

NCCN guidelines insights: B-cell lymphomas, version 3.2019: featured updates to the NCCN guidelines

AD Zelenetz, LI Gordon, JS Abramson… - Journal of the National …, 2019 - jnccn.org
Diffuse large B-cell lymphomas (DLBCLs) and follicular lymphoma (FL) are the most
common subtypes of B-cell non-Hodgkin's lymphomas in adults. Histologic transformation of …