Pancreatic islet transplantation in humans: recent progress and future directions

MR Rickels, RP Robertson - Endocrine reviews, 2019 - academic.oup.com
Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

The role of total pancreatectomy and islet autotransplantation for chronic pancreatitis

JJ Blondet, AM Carlson, T Kobayashi, T Jie… - Surgical Clinics of North …, 2007 - Elsevier
Total pancreatectomy and islet autotransplantation are done for chronic pancreatitis with
intractable pain when other treatment measures have failed, allowing insulin secretory …

Total pancreatectomy and islet autotransplantation for chronic pancreatitis

DER Sutherland, DM Radosevich, MD Bellin… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Total pancreatectomy (TP) with intraportal islet autotransplantation (IAT)
can relieve pain and preserve β-cell mass in patients with chronic pancreatitis (CP) when …

Total pancreatectomy and islet autotransplantation in children for chronic pancreatitis: indication, surgical techniques, postoperative management, and long-term …

S Chinnakotla, MD Bellin, SJ Schwarzenberg… - Annals of …, 2014 - journals.lww.com
Objective: Describe the surgical technique, complications, and long-term outcomes of total
pancreatectomy and islet autotransplantation (TP-IAT) in a large series of pediatric patients …

Factors predicting outcomes after a total pancreatectomy and islet autotransplantation lessons learned from over 500 cases

S Chinnakotla, GJ Beilman, TB Dunn, MD Bellin… - Annals of …, 2015 - journals.lww.com
Objective: Our objective was to analyze factors predicting outcomes after a total
pancreatectomy and islet autotransplantation (TP-IAT). Background: Chronic pancreatitis …

Total pancreatectomy and islet autotransplantation in chronic pancreatitis: recommendations from PancreasFest

MD Bellin, ML Freeman, A Gelrud, A Slivka, A Clavel… - Pancreatology, 2014 - Elsevier
Total pancreatectomy with islet autotransplantation (TPIAT) is a surgical procedure used to
treat severe complications of chronic pancreatitis or very high risk of pancreatic cancer while …

Long-term outcomes after total pancreatectomy and islet cell autotransplantation: is it a durable operation?

GC Wilson, JM Sutton, DE Abbott, MT Smith… - Annals of …, 2014 - journals.lww.com
Objective: Total pancreatectomy and islet cell autotransplantation (TPIAT) has been
increasingly utilized for the management of chronic pancreatitis (CP) with early success …

Total pancreatectomy with islet autotransplantation as an alternative to high-risk pancreatojejunostomy after pancreaticoduodenectomy: a prospective randomized trial

G Balzano, A Zerbi, F Aleotti, G Capretti, R Melzi… - 2023 - journals.lww.com
Objective: To compare pancreaticoduodenectomy (PD) and total pancreatectomy (TP) with
islet autotransplantation (IAT) in patients at high risk of postoperative pancreatic fistula …

Quality of life improves for pediatric patients after total pancreatectomy and islet autotransplant for chronic pancreatitis

MD Bellin, ML Freeman, SJ Schwarzenberg… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: Total pancreatectomy (TP) and islet autotransplant (IAT) have been
used to treat patients with painful chronic pancreatitis. Initial studies indicated that most …

Are there still indications for total pancreatectomy?

M Del Chiaro, E Rangelova, R Segersvärd, U Arnelo - Updates in surgery, 2016 - Springer
Total pancreatectomy is associated with short-and long-term high complication rate and
without evidence of oncologic advantages. Several metabolic consequences are co-related …