Cholesterol stiffening of lipid membranes
Biomembrane order, dynamics, and other essential physicochemical parameters are
controlled by cholesterol, a major component of mammalian cell membranes. Although …
controlled by cholesterol, a major component of mammalian cell membranes. Although …
[HTML][HTML] Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels
As described in the literature the interaction between cholesterol and membrane proteins
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …
Spontaneous curvature, differential stress, and bending modulus of asymmetric lipid membranes
Lipid bilayers can exhibit asymmetric states, in which the physical characteristics of one
leaflet differ from those of the other. This most visibly manifests in a different lipid …
leaflet differ from those of the other. This most visibly manifests in a different lipid …
Distribution of cholesterol in asymmetric membranes driven by composition and differential stress
Many lipid membranes of eukaryotic cells are asymmetric, which means the two leaflets
differ in at least one physical property, such as lipid composition or lateral stress …
differ in at least one physical property, such as lipid composition or lateral stress …
Nanoscale dynamics of cholesterol in the cell membrane
K Pinkwart, F Schneider, M Lukoseviciute… - Journal of Biological …, 2019 - ASBMB
Cholesterol constitutes∼ 30–40% of the mammalian plasma membrane, a larger fraction
than of any other single component. It is a major player in numerous signaling processes as …
than of any other single component. It is a major player in numerous signaling processes as …
Requirement of Cholesterol for Calcium‐Dependent Vesicle Fusion by Strengthening Synaptotagmin‐1‐Induced Membrane Bending
Cholesterol is essential for neuronal activity and function. Cholesterol depletion in the
plasma membrane impairs synaptic transmission. However, the molecular mechanisms by …
plasma membrane impairs synaptic transmission. However, the molecular mechanisms by …
Simulations of asymmetric membranes illustrate cooperative leaflet coupling and lipid adaptability
M Blumer, S Harris, M Li, L Martinez… - Frontiers in Cell and …, 2020 - frontiersin.org
Biological membranes are composed of lipid bilayers that are often asymmetric with regards
to the lipid composition and/or aqueous solvent they separate. Studying lipid asymmetry …
to the lipid composition and/or aqueous solvent they separate. Studying lipid asymmetry …
Simulated dynamic cholesterol redistribution favors membrane fusion pore constriction
Endo-and exocytosis proceed through a highly strained membrane fusion pore topology
regardless of the aiding protein machinery. The membrane's lipid components bias fusion …
regardless of the aiding protein machinery. The membrane's lipid components bias fusion …
Investigation of the domain line tension in asymmetric vesicles prepared via hemifusion
TA Enoki, J Wu, FA Heberle, GW Feigenson - Biochimica et Biophysica …, 2021 - Elsevier
The plasma membrane (PM) is asymmetric in lipid composition. The distinct and
characteristic lipid compositions of the exoplasmic and cytoplasmic leaflets lead to different …
characteristic lipid compositions of the exoplasmic and cytoplasmic leaflets lead to different …
Designing a useful lipid raft model membrane for electrochemical and surface analytical studies
M Zaborowska, D Dziubak, D Matyszewska, S Sek… - Molecules, 2021 - mdpi.com
A model biomimetic system for the study of protein reconstitution or drug interactions should
include lipid rafts in the mixed lipid monolayer, since they are usually the domains …
include lipid rafts in the mixed lipid monolayer, since they are usually the domains …