Ocular drug delivery barriers—role of nanocarriers in the treatment of anterior segment ocular diseases

RD Bachu, P Chowdhury, ZHF Al-Saedi, PK Karla… - Pharmaceutics, 2018 - mdpi.com
Ocular drug delivery is challenging due to the presence of anatomical and physiological
barriers. These barriers can affect drug entry into the eye following multiple routes of …

Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease

B Fonseca-Santos, MPD Gremião… - International Journal of …, 2015 - Taylor & Francis
Alzheimer's disease is a neurological disorder that results in cognitive and behavioral
impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs …

Nanostructured lipid carriers system: recent advances in drug delivery

MA Iqbal, S Md, JK Sahni, S Baboota… - Journal of drug …, 2012 - Taylor & Francis
Nanostructured lipid carrier (NLC) is second generation smarter drug carrier system having
solid matrix at room temperature. This carrier system is made up of physiological …

Recent perspectives in ocular drug delivery

R Gaudana, J Jwala, SHS Boddu, AK Mitra - Pharmaceutical research, 2009 - Springer
Anatomy and physiology of the eye makes it a highly protected organ. Designing an effective
therapy for ocular diseases, especially for the posterior segment, has been considered as a …

Developments of Polysorbate (Tween) based microemulsions: Preclinical drug delivery, toxicity and antimicrobial applications

G Kaur, SK Mehta - International journal of pharmaceutics, 2017 - Elsevier
The present review deals with the progress of Polysorbates (Tween) based microemulsions
in drug delivery. PEGylated Sorbitan Fatty Acid Esters (Tweens/Polysorbates) are one of the …

Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs): recent advances in drug delivery

G Yoon, JW Park, IS Yoon - Journal of Pharmaceutical Investigation, 2013 - Springer
Solid lipid-based nanoparticles (SLBNs) were developed as potential alternatives to other
conventional drug delivery systems such as polymeric nanoparticles, liposomes, and …

Recent advances in topical ocular drug delivery

VK Yellepeddi, S Palakurthi - Journal of Ocular Pharmacology and …, 2016 - liebertpub.com
Topical ocular drug delivery has been considered to be an ideal route of administration for
treatment of ocular diseases related to the anterior segment of the eye. However, topical …

Nanomedicines for ocular NSAIDs: safety on drug delivery

J Araújo, E Gonzalez, MA Egea, ML Garcia… - … , Biology and Medicine, 2009 - Elsevier
The eyes are among the most readily accessible organs in terms of location in the body, yet
drug delivery to eye tissues is particularly problematic. Poor bioavailability of drugs from …

Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system

Q Luo, J Zhao, X Zhang, W Pan - International journal of pharmaceutics, 2011 - Elsevier
The objective of the present investigation was to explore the potential of the Chitosan
Oligosaccharides (COS)-coated NLC (nanostructured lipid carrier) for ocular drug delivery …

Liposome coated with low molecular weight chitosan and its potential use in ocular drug delivery

N Li, C Zhuang, M Wang, X Sun, S Nie… - International journal of …, 2009 - Elsevier
In this study liposome coated with low molecular weight chitosan (LCH) was proposed and
investigated its in vitro and in vivo properties, and its potential use in ocular drug delivery …