[HTML][HTML] Current trends in drug metabolism and pharmacokinetics

Y Li, Q Meng, M Yang, D Liu, X Hou, L Tang… - … Pharmaceutica Sinica B, 2019 - Elsevier
Pharmacokinetics (PK) is the study of the absorption, distribution, metabolism, and excretion
(ADME) processes of a drug. Understanding PK properties is essential for drug development …

[HTML][HTML] The effect of sildenafil on rats with adenine—Induced chronic kidney disease

BH Ali, M Al Za'abi, SA Adham, Y Al Suleimani… - Biomedicine & …, 2018 - Elsevier
The erectile dysfunction drug sildenafil has cardiopulmonary protective actions, and a
nephroprotective action in cisplatin and ischemia-reperfusion–induced acute kidney injury …

[HTML][HTML] Gum acacia improves renal function and ameliorates systemic inflammation, oxidative and nitrosative stress in streptozotocin-induced diabetes in rats with …

A Za'abi, S Al Salam, Y Al Suleimani, P Manoj… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: The effect of treatment with gum acacia (GA), a prebiotic shown
previously to ameliorate chronic kidney disease (CKD), in diabetic and non–diabetic rats …

Combined toxicity of outdoor air pollution on kidney function among adult women in Mianyang City, southwest China

HH Wang, SC Zhang, J Wang, X Chen, H Yin… - Chemosphere, 2020 - Elsevier
Environmental pollution is a risk factor for kidney dysfunction. However, the combined
toxicity of air pollutants on kidney function is scarce. We estimated the relationship between …

Anemoside B4 protects rat kidney from adenine‐induced injury by attenuating inflammation and fibrosis and enhancing podocin and nephrin expression

Q Gong, LL He, ML Wang, H Ouyang… - Evidence‐Based …, 2019 - Wiley Online Library
Anemoside B4 (B4) isolated from Radix Pulsatilla has anti‐inflammatory activities in the
colon and antitumor effects. However, its role in the prevention and treatment of kidney injury …

Emerging roles of aryl hydrocarbon receptors in the altered clearance of drugs during chronic kidney disease

T Santana Machado, C Cerini, S Burtey - Toxins, 2019 - mdpi.com
Chronic kidney disease (CKD) is a major public health problem, since 300,000,000 people
in the world display a glomerular filtration rate (GFR) below 60 mL/min/1.73 m2. Patients …

Gum arabic reduces inflammation, oxidative, and nitrosative stress in the gastrointestinal tract of mice with chronic kidney disease

BH Ali, M Al Za'abi, Y Al Suleimani, P Manoj… - Naunyn-Schmiedeberg's …, 2020 - Springer
The aim of this study was to investigate some biochemical indices of inflammation and
oxidative and nitrosative stresses in the gastrointestinal tract of mice with experimental …

Atrazine-induced environmental nephrosis was mitigated by lycopene via modulating nuclear xenobiotic receptors-mediated response

J Xia, J Lin, XN Li, C Zhang, N Li, ZH Du, YH Li… - The Journal of nutritional …, 2018 - Elsevier
The burden and morbidity of environmental nephrosis is increasing globally. Atrazine (ATR)
and degradation products in the environment are considered key determinants of nephrosis …

[HTML][HTML] The effect of swimming exercise on adenine-induced kidney disease in rats, and the influence of curcumin or lisinopril thereon

BH Ali, T Karaca, Y Al Suleimani, M Al Za'abi… - PloS one, 2017 - journals.plos.org
Patients with chronic kidney disease (CKD) have been reported to benefit from different
types of exercises. It has also been shown that the ACE inhibitor lisinopril, and the natural …

[PDF][PDF] Therapeutic effects of Origanum majorana and propolis against nephrotoxicity induced by adenine

HM Abdelsalam, AA Diab, MH Zahra, S Eldehamy… - Biol Eng …, 2019 - siriusstore.com
The present study assessed the effect of marjoram, propolis, and their combination against
adenine induced chronic kidney disease (CKD) and renal dysfunction in male albino rats …