Peptide-based liquid droplets as emerging delivery vehicles

J Liu, E Spruijt, A Miserez, R Langer - Nature Reviews Materials, 2023 - nature.com
Peptides are small yet versatile building blocks of biomaterials. This Comment highlights
recent progress in the design of liquid-like microdroplets, or coacervates, based on peptides …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Recombinant protein-based injectable materials for biomedical applications

CG Garcia, SS Patkar, B Wang, R Abouomar… - Advanced Drug Delivery …, 2023 - Elsevier
Injectable nanocarriers and hydrogels have found widespread use in a variety of biomedical
applications such as local and sustained biotherapeutic cargo delivery, and as cell …

Radioiodine based biomedical carriers for cancer theranostics

J Guo, H Xiong, H Liu, T Zhang, X Sun - Coordination Chemistry Reviews, 2023 - Elsevier
Theranostics, a promising modern concept combining diagnostic capabilities and
therapeutic effects, has been used for optimizing and personalizing the treatment of many …

Instructional materials that control cellular activity through synthetic Notch receptors

JC Lee, HJ Brien, BL Walton, ZM Eidman, S Toda… - Biomaterials, 2023 - Elsevier
The field of regenerative engineering relies primarily on the dual technical platforms of cell
selection/conditioning and biomaterial fabrication to support directed cell differentiation. As …

Temperature-Responsive Bottlebrush Polymers Deliver a Stress-Regulating Agent In Vivo for Prolonged Plant Heat Stress Mitigation

Y Zhang, L Fu, MR Martinez, H Sun… - ACS Sustainable …, 2023 - ACS Publications
Anticipated increases in the frequency and intensity of extreme temperatures will damage
crops. Methods that efficiently deliver stress-regulating agents to crops can mitigate these …

Nanotechnology for next-generation cancer immunotherapy: State of the art and future perspectives

Y Chen - Journal of Controlled Release, 2023 - Elsevier
Over the past decade, immunotherapy aiming to activate an effective antitumor immune
response has ushered in a new era of cancer treatment. However, the efficacy of cancer …

Programmability and biomedical utility of intrinsically-disordered protein polymers

MC Giraldo-Castano, KA Littlejohn… - Advanced Drug Delivery …, 2024 - Elsevier
Intrinsically disordered proteins (IDPs) exhibit molecular-level conformational dynamics that
are functionally harnessed across a wide range of fascinating biological phenomena. The …

Therapeutic synthetic and natural materials for immunoengineering

A Slezak, K Chang, S Hossainy, A Mansurov… - Chemical Society …, 2024 - pubs.rsc.org
Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …

Molecular Complementarity of Proteomimetic Materials for Target‐Specific Recognition and Recognition‐Mediated Complex Functions

M Kim, H Jo, GY Jung, SS Oh - Advanced Materials, 2023 - Wiley Online Library
As biomolecules essential for sustaining life, proteins are generated from long chains of 20
different α‐amino acids that are folded into unique 3D structures. In particular, many proteins …