Bovine herpesvirus 1 (BoHV-1), classified as an alphaherpesvirus, is a major pathogen of
cattle. Primary infection is accompanied by various clinical manifestations such as infectious …

Vaccination is arguably the most cost-effective preventative measure against infectious
diseases. While vaccines have been successfully developed against certain viruses (eg …

Infection of cattle by bovine herpesvirus type 1 (BHV-1) can lead to upper respiratory tract
disorders, conjunctivitis, genital disorders and immune suppression. BHV-1-induced …

Human adenoviral (HAd) vectors have demonstrated great potential as vaccine vectors.
Preclinical and clinical studies have demonstrated the feasibility of vector design, robust …

The bovine respiratory disease complex continues to be an economically important
syndrome in an era when immunologic control is likely to become increasingly important …

Infectious laryngotracheitis (ILT) is a highly contagious acute respiratory disease of chickens
caused by infectious laryngotracheitis virus (ILTV). Currently, modified live ILTV vaccines are …

The recent advances in molecular genetics, pathogenesis and immunology have provided
an optimal framework for developing novel approaches in the rational design of vaccines …

Although recombinant human adenovirus (HAV)-based vectors offer several advantages for
somatic gene therapy and vaccination over other viral vectors, it would be desirable to …

Abstract Background Rift Valley Fever (RVF) is a viral zoonosis that historically affects
livestock production and human health in sub-Saharan Africa, though epizootics have also …

Bovine herpesvirus-1 (BHV-1) is a major cause of respiratory tract diseases in cattle.
Vaccination of cattle against BHV-1 is a high priority. A major concern of currently modified …