Background Melanoma is one of the most aggressive forms of skin cancer, with the potential
to metastasise to other parts of the body via the lymphatic system and the bloodstream …

Metastatic melanoma (MM) is a fatal disease with a rapid systemic dissemination. This study
was conducted to investigate the metastatic behavior, timing, patterns, survival, and …

Metastasis represents the end product of an elaborate biological process, which is
determined by a complex interplay between metastatic tumour cells, host factors and …

Background This study identified sex differences in progression of cutaneous melanoma.
Methodology/Principal Findings Of 7,338 patients who were diagnosed as an invasive …

Background: Cutaneous melanoma can metastasise haematogenously and/or
lymphogenously to form satellite/in-transit, lymph node or distant metastasis. This study …

Nearly one-third of all melanoma patients will experience disease recurrence and the
majority of the relapses eventually develop metastatic disease as a consequence of disease …

Importance The lymphatic and the hematogenous pathways have been proposed for
disease progression in cutaneous melanoma, but association with recurrence has not been …

Objective To investigate stage-specific survival from diagnosis, stage-specific disease
recurrence, and post-recurrence survival in patients diagnosed with localized and regionally …

Background Melanoma is a tumour with a very variable progression. Whilst some
melanomas grow slowly over many years, others can reach several millimetres in thickness …

Background While curable at early stages, few treatment options exist for advanced
melanoma. Currently, no consensus exists regarding the optimal surveillance strategy for …