Anti-TNFα in inflammatory bowel disease: from originators to biosimilars

Z Zeng, H Lin, M Jiang, J Yuan, X Li, Y Jia… - Frontiers in …, 2024 - frontiersin.org
The introduction of anti-tumor necrosis factor α (TNFα) biologics significantly innovated
inflammatory bowel disease (IBD) treatment and increased medical costs. The recent …

Patient preferences for adalimumab in inflammatory bowel disease: a nationwide study from the GETAID

B Caron, P Seksik, A Buisson, P Wils… - Therapeutic …, 2024 - journals.sagepub.com
Background: Several adalimumab preparations are now available for patients with
inflammatory bowel disease (IBD). Comparative satisfaction and tolerability are unknown …

Trends in Targeted Therapy Usage in Inflammatory Bowel Disease: TRENDY Study of ENEIDA

C Gómez-Labrador, E Ricart, M Iborra, E Iglesias… - Pharmaceutics, 2024 - mdpi.com
Markers that allow for the selection of tailored treatments for individual patients with
inflammatory bowel diseases (IBD) are yet to be identified. Our aim was to describe trends in …

Drug survival and safety of biosimilars and originator adalimumab in the treatment of psoriasis: a multinational cohort study

DB Phan, H Jourdain, A González-Quesada… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Psoriasis is a chronic inflammatory skin disease. Adalimumab is an effective but
previously expensive biological treatment for psoriasis. The introduction of biosimilars …

Adalimumab Persistence and Its Biosimilar in Inflammatory Bowel Disease: A Real-World Study

MC Fernández-Cano, AJ Fernández-Cano… - Journal of Clinical …, 2024 - mdpi.com
Adalimumab biosimilar experience is still recent. Interchangeability differences could reduce
persistence times. Our goal was to compare biosimilar persistence differences with a …

Drug Survival and Safety of Biosimilars Compared with Originator Adalimumab for Psoriasis: A Multinational Cohort Study

DB Phan, H Jourdain… - British Journal of …, 2024 - academic.oup.com
Background The lack of evidence under routine clinical settings limited the widespread
adoption of adalimumab biosimilars for psoriasis treatment. Objective This study compared …

[HTML][HTML] Real-world experience and long-term outcomes of a mandatory non-medical switch of adalimumab originator to biosimilars in inflammatory bowel disease

JLC Kiow, T Hoang, HK Bedi… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Over the last decade, the treatment options for inflammatory bowel disease
(IBD) have significantly progressed with the emergence of new medications designed to …

阿达木单抗生物类似药是否可进行临床互换用药: 基于系统评价与Meta 分析的证据

胡杨, 宋再伟, 高媛, 冉怡雯, 姜丹… - … 临床药理学与治疗学, 2024 - manu41.magtech.com.cn
目的: 系统评价阿达木单抗生物类似药临床互换用药的有效性, 安全性与免疫原性,
为临床互换用药提供循证参考. 方法: 系统检索Pubmed, Embase, Cochrane Library, CNKI …

Clinical Guide to Navigating the Landscape of Biosimilars for Inflammatory Bowel Disease

S Bhat, SV Kane - Gastroenterology & Hepatology, 2024 - pmc.ncbi.nlm.nih.gov
Annual out-of-pocket expenditures for patients with inflammatory bowel disease (IBD) are
estimated to be as high as $41,000, with medications, such as biologics, being one of the …

Can adalimumab biosimilars be clinically interchanged: evidence based on a systematic review and Meta-analysis

Y HU, Z SONG, Y GAO, Y RAN… - Chinese Journal of …, 2024 - manu41.magtech.com.cn
AIM: To systematically evaluate the clinical interchangeability of adalimumab biosimilars in
terms of efficacy, safety, and immunogenicity, and to provide evidence-based reference for …