Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

[HTML][HTML] Computerized cell tracking: Current methods, tools and challenges

N Emami, Z Sedaei, R Ferdousi - Visual Informatics, 2021 - Elsevier
In developmental biology, knowledge of cell structure and their (morpho) dynamic behavior,
leads to a comprehensive understanding of their conducts and the mechanisms in which …

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors

J Möller, A Isbilir, T Sungkaworn, B Osberg… - Nature Chemical …, 2020 - nature.com
G-protein-coupled receptors (GPCRs) are key signaling proteins that mostly function as
monomers, but for several receptors constitutive dimer formation has been described and in …

Automated nanoscale absolute accuracy alignment system for transfer printing

J McPhillimy, D Jevtics, BJE Guilhabert… - ACS applied nano …, 2020 - ACS Publications
The heterogeneous integration of micro-and nanoscale devices with on-chip circuits and
waveguide platforms is a key enabling technology, with wide-ranging applications in areas …

Single viruses on the fluorescence microscope: imaging molecular mobility, interactions and structure sheds new light on viral replication

N Parveen, D Borrenberghs, S Rocha, J Hendrix - Viruses, 2018 - mdpi.com
Viruses are simple agents exhibiting complex reproductive mechanisms. Decades of
research have provided crucial basic insights, antiviral medication and moderately …

Image restoration and analysis of influenza virions binding to membrane receptors reveal adhesion-strengthening kinetics

DW Lee, HL Hsu, KB Bacon, S Daniel - PLoS One, 2016 - journals.plos.org
With the development of single-particle tracking (SPT) microscopy and host membrane
mimics called supported lipid bilayers (SLBs), stochastic virus-membrane binding …

Fluorescence techniques in developmental biology

S Veerapathiran, T Wohland - Journal of biosciences, 2018 - Springer
Advanced fluorescence techniques, commonly known as the F-techniques, measure the
kinetics and the interactions of biomolecules with high sensitivity and spatiotemporal …

TRICK: a single-molecule method for imaging the first round of translation in living cells and animals

JM Halstead, JH Wilbertz, F Wippich, T Lionnet… - Methods in …, 2016 - Elsevier
The life of an mRNA is dynamic within a cell. The development of quantitative fluorescent
microscopy techniques to image single molecules of RNA has allowed many aspects of the …

Single-particle tracking for studying nanomaterial dynamics: applications and fundamentals in drug delivery

E Zagato, K Forier, T Martens, K Neyts… - …, 2014 - Taylor & Francis
Many macromolecular therapeutics could potentially treat genetic disorders and cancer.
They have, however, not yet reached the clinical stage owing to a lack of suitable carriers …

Heterologous calcium-dependent inactivation of Orai1 by neighboring TRPV1 channels modulates cell migration and wound healing

CE Bastián-Eugenio, A Bohórquez-Hernández… - Communications …, 2019 - nature.com
Store-operated calcium entry (SOCE) is an essential calcium influx mechanism in animal
cells. One of the most important auto regulatory control systems involves calcium-dependent …