CircRNA in cancer: fundamental mechanism and clinical potential
Abstract Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are
formed in a circular conformation via non-canonical splicing or back-splicing events …
formed in a circular conformation via non-canonical splicing or back-splicing events …
Circular RNAs in cancer: biogenesis, function, and clinical significance
J Li, D Sun, W Pu, J Wang, Y Peng - Trends in cancer, 2020 - cell.com
Circular RNA (circRNA) is a class of single-stranded molecules with tissue/development-
specific expression patterns. Unlike linear RNA, circRNA forms a covalently closed loop …
specific expression patterns. Unlike linear RNA, circRNA forms a covalently closed loop …
circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity
Circular RNAs (circRNA) are a class of covalently closed single-stranded RNAs that have
been implicated in cancer progression. Here we identify circNDUFB2 to be downregulated …
been implicated in cancer progression. Here we identify circNDUFB2 to be downregulated …
N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non …
Z Liu, T Wang, Y She, K Wu, S Gu, L Li, C Dong… - Molecular cancer, 2021 - Springer
Background An in-depth understanding of immune evasion mechanisms in tumors is crucial
to overcome resistance and enable innovative advances in immunotherapy. Circular RNAs …
to overcome resistance and enable innovative advances in immunotherapy. Circular RNAs …
N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis
RX Chen, X Chen, LP Xia, JX Zhang, ZZ Pan… - Nature …, 2019 - nature.com
Circular RNAs (circRNAs) have been implicated in cancer progression through largely
unknown mechanisms. Herein, we identify an N 6-methyladenosine (m6A) modified …
unknown mechanisms. Herein, we identify an N 6-methyladenosine (m6A) modified …
Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma
X Zhang, Y Xu, L Ma, K Yu, Y Niu, X Xu… - Cancer …, 2022 - Wiley Online Library
Background Resistance to ferroptosis, a regulated cell death caused by iron‐dependent
excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma …
excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma …
Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma
T Liu, C Han, P Fang, Z Ma, X Wang, H Chen… - Journal of hematology & …, 2022 - Springer
Background Besides featured glucose consumption, recent studies reveal that cancer cells
might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); …
might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); …
[HTML][HTML] Circular RNAs in cancer
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1
Circular RNAs (circRNAs) are identified as vital regulators in a variety of cancers. However,
the role of circRNA in lung squamous cell carcinoma (LUSC) remains largely unknown …
the role of circRNA in lung squamous cell carcinoma (LUSC) remains largely unknown …
CircRNAs and cancer: biomarkers and master regulators
E Arnaiz, C Sole, L Manterola, L Iparraguirre… - Seminars in cancer …, 2019 - Elsevier
Circular RNAs (circRNAs) are a novel class of regulatory RNAs that despite being relatively
abundant have only recently begun to be explored. There are many thousands of genes that …
abundant have only recently begun to be explored. There are many thousands of genes that …