BACKGROUND: Snake venoms are rich sources of bioactive molecules, and several venom-
derived proteins have entered clinical trials for use in ischemic disorders; however, late …

Ontogenetic changes in venom composition have been described in Bothrops snakes, but
only a few studies have attempted to identify the targeted paralogues or the molecular …

Background: Consumption coagulopathy and hemorrhagic syndrome are the typical
features of Bothrops sp. snake envenoming. In contrast, B. lanceolatus envenoming can …

PEGylation was firstly described around 50 years ago and has been used for more than 30
years as a strategy to improve the drugability of biopharmaceuticals. However, it remains …

This study reports the isolation and biochemical characterization of two different serine
proteases from Bothrops pirajai snake venom, thus providing a comparative analysis of the …

In the present study, a thrombin-like enzyme named BpSP-I was isolated from Bothrops
pauloensis snake venom and its biochemical, enzymatic and pharmacological …

The thrombin-like enzyme from Bothrops barnetti named barnettobin was purified. We report
some biochemical features of barnettobin including the complete amino acid sequence that …

This paper presents a novel serine protease (SP) isolated from Bothrops pirajai, a
venomous snake found solely in Brazil that belongs to the Viperidae family. The identified …

Protein glycosylation represents one of the most important post-translational events, and is a
mean of diversifying a protein without recourse to the genome. The venoms produced by …

Background: Bitis arietans is a venomous snake found in sub-Saharan Africa and in parts of
Morocco and Saudi Arabia. The envenomation is characterized by local and systemic …