Dynamics of neuron-like excitable Josephson junctions coupled by a metal oxide memristive synapse

F Wu, Z Yao - Nonlinear Dynamics, 2023 - Springer
Transition of firing modes via synapse is a crucial step in neural coding. The
neuron/synapse-like circuits have been proposed to simulate neural behaviors and …

16p11. 2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro

M Sundberg, H Pinson, RS Smith, KD Winden… - Nature …, 2021 - nature.com
Reciprocal copy number variations (CNVs) of 16p11. 2 are associated with a wide spectrum
of neuropsychiatric and neurodevelopmental disorders. Here, we use human induced …

Biophysical models of intrinsic homeostasis: Firing rates and beyond

N Niemeyer, JH Schleimer, S Schreiber - Current Opinion in Neurobiology, 2021 - Elsevier
In view of ever-changing conditions both in the external world and in intrinsic brain states,
maintaining the robustness of computations poses a challenge, adequate solutions to which …

Transitions between classes of neuronal excitability and bifurcations induced by autapse

Z Zhao, H Gu - Scientific Reports, 2017 - nature.com
Neuronal excitabilities behave as the basic and important dynamics related to the transitions
between firing and resting states, and are characterized by distinct bifurcation types and …

Excitatory autapse induces different cases of reduced neuronal firing activities near Hopf bifurcation

Z Zhao, L Li, H Gu - Communications in Nonlinear Science and Numerical …, 2020 - Elsevier
Excitatory autapse with short time delay can lower the firing frequency of spiking behaviors
near subcritical Hopf bifurcation, which is interpreted with type II phase response curve …

Cost-efficient FPGA implementation of a biologically plausible dopamine neural network and its application

S Yang, J Wang, Q Lin, B Deng, X Wei, C Liu, H Li - Neurocomputing, 2018 - Elsevier
Dopamine neurons play an essential role in terms of cognitive coordination and executive
functions, which has been investigated in the therapy of multiple psychiatric and …

Dynamical mechanism of hyperpolarization-activated non-specific cation current induced resonance and spike-timing precision in a neuronal model

Z Zhao, L Li, H Gu - Frontiers in Cellular Neuroscience, 2018 - frontiersin.org
Hyperpolarization-activated cyclic nucleotide-gated cation current (I h) plays important roles
in the achievement of many physiological/pathological functions in the nervous system by …

Dynamical ventral tegmental area circuit mechanisms of alcohol‐dependent dopamine release

M Di Volo, EO Morozova, CC Lapish… - European Journal of …, 2019 - Wiley Online Library
A large body of data has identified numerous molecular targets through which ethanol
(EtOH) acts on brain circuits. Yet how these multiple mechanisms interact to result in …

Excitability and threshold mechanism for enhanced neuronal response induced by inhibition preceding excitation

H Ma, B Jia, Y Li, H Gu - Neural Plasticity, 2021 - Wiley Online Library
Postinhibitory facilitation (PIF) of neural firing presents a paradoxical phenomenon that the
inhibitory effect induces enhancement instead of reduction of the firing activity, which plays …

Biophysical modeling suggests optimal drug combinations for improving the efficacy of GABA agonists after traumatic brain injuries

SK Sudhakar, TJ Choi, OJ Ahmed - Journal of Neurotrauma, 2019 - liebertpub.com
Traumatic brain injuries (TBI) lead to dramatic changes in the surviving brain tissue. Altered
ion concentrations, coupled with changes in the expression of membrane-spanning …