An optimized live bacterial delivery vehicle safely and efficaciously delivers bacterially transcribed therapeutic nucleic acids
DSO Mora, M Cox, F Magunda… - Engineering in Life …, 2023 - Wiley Online Library
There is an unmet need for delivery platforms that realize the full potential of next‐
generation nucleic acid therapeutics. The in vivo usefulness of current delivery systems is …
generation nucleic acid therapeutics. The in vivo usefulness of current delivery systems is …
Who's afraid of epigenetics? Habits, instincts, and Charles Darwin's evolutionary theory
M Portera, M Mandrioli - History and Philosophy of the Life Sciences, 2021 - Springer
Our paper aims at bringing to the fore the crucial role that habits play in Charles Darwin's
theory of evolution by means of natural selection. We have organized the paper in two steps …
theory of evolution by means of natural selection. We have organized the paper in two steps …
Two parallel sRNA amplification cycles contribute to RNAi inheritance in C. elegans
JPT Ouyang, W Zhang, G Seydoux - BioRxiv, 2021 - biorxiv.org
RNA-mediated interference (RNAi) is a conserved mechanism that uses small RNAs
(sRNAs) to tune gene expression. In C. elegans, exposure to dsRNA induces the production …
(sRNAs) to tune gene expression. In C. elegans, exposure to dsRNA induces the production …
A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor …
T Wiesenfahrt, J Duanmu, F Snider… - G3: Genes …, 2018 - academic.oup.com
The ELT-2 GATA factor normally functions in differentiation of the C. elegans endoderm,
downstream of endoderm specification. We have previously shown that, if ELT-2 is …
downstream of endoderm specification. We have previously shown that, if ELT-2 is …
Epigenetic transgenerational effects on RNAi in Arabidopsis
Q Hu, J Ailhas, T Blevins, U Klahre, F Vazquez… - bioRxiv, 2020 - biorxiv.org
Epigenetic states and even certain environmental responses in nematodes, mammals and
seed plants can be inherited over successive generations. These transgenerational effects …
seed plants can be inherited over successive generations. These transgenerational effects …
An optimized live bacterial delivery platform for the production and delivery of therapeutic nucleic acids and proteins
DSO Mora, M Cox, F Magunda, AB Williams, L Linke - bioRxiv, 2021 - biorxiv.org
There is an unmet need for delivery platforms that realize the full potential of next-generation
therapeutic and vaccine technologies, especially those that require intracellular delivery of …
therapeutic and vaccine technologies, especially those that require intracellular delivery of …
Are Habits Inherited? A Possible Epigenetic Route from Charles Darwin to the Contemporary Debate 1
M Portera, M Mandrioli - Habit and the History of Philosophy, 2022 - api.taylorfrancis.com
What is a habit? What do habitual processes and evolutionary theory have to do with each
other and what is the role played by habitual processes in heredity? It is safe to say that the …
other and what is the role played by habitual processes in heredity? It is safe to say that the …
[PDF][PDF] Epigenetic transgenerational effects on RNAi in Arabidopsis
MF Mette, F Meins Jr - scholar.archive.org
Epigenetic states and even certain environmental responses in nematodes, mammals and
seed plants can be inherited over successive generations. These transgenerational effects …
seed plants can be inherited over successive generations. These transgenerational effects …