[HTML][HTML] Intake of ω-6 polyunsaturated fatty acid-rich vegetable oils and risk of lifestyle diseases
T Yamashima, T Ota, E Mizukoshi, H Nakamura… - Advances in …, 2020 - Elsevier
Although excessive consumption of deep-fried foods is regarded as 1 of the most important
epidemiological factors of lifestyle diseases such as Alzheimer's disease, type 2 diabetes …
epidemiological factors of lifestyle diseases such as Alzheimer's disease, type 2 diabetes …
Implication of vegetable oil-derived hydroxynonenal in the lysosomal cell death for lifestyle-related diseases
T Yamashima - Nutrients, 2023 - mdpi.com
Lysosomes are membrane-bound vesicular structures that mediate degradation and
recycling of damaged macromolecules and organelles within the cell. For ensuring the place …
recycling of damaged macromolecules and organelles within the cell. For ensuring the place …
Hydroxynonenal causes Langerhans cell degeneration in the pancreas of Japanese macaque monkeys
P Boontem, T Yamashima - PLoS One, 2021 - journals.plos.org
Background For their functions of insulin biosynthesis and glucose-and fatty acid-mediated
insulin secretion, Langerhans β-cells require an intracellular milieu rich in oxygen. This …
insulin secretion, Langerhans β-cells require an intracellular milieu rich in oxygen. This …
[PDF][PDF] Hydroxynonenal makes Alzheimer pathology without amyloid β: Which is a real culprit
T Yamashima - J. Alzheimers. Dis. Park, 2021 - arimatu-clinic.com
Currently, about 50 million people worldwide are suffering from Alzheimer's disease, and
most of the therapeutic drugs including novel antibodies against amyloid β or Tau proteins …
most of the therapeutic drugs including novel antibodies against amyloid β or Tau proteins …
[PDF][PDF] Possible prevention of Alzheimer's disease by aldehyde dehydrogenase: A perspective review
T Yamashima - J Alzheimers Dis Parkinsonism, 2020 - arimatu-clinic.com
Investigating the mechanism of neuronal death in Alzheimer's disease is difficult, because
only a tiny percentage of neurons are degenerating at any time point during the long …
only a tiny percentage of neurons are degenerating at any time point during the long …