Parkinson's disease (PD) is a common neurodegenerative disorder. While a number of
nonmotor manifestations arise, the typical clinical features involve a movement disorder …

Adenosine is a ubiquitous endogenous autacoid whose effects are triggered through the
enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Due to the rapid …

Since 2006, several longitudinal studies have assessed environmental or behavioural
factors that seem to modify the risk of developing Parkinson's disease. Increased risk of …

Most individuals adjust their caffeine intake according to the objective and subjective effects
induced by the methylxanthine. However, to reach the desired effects, the quantity of …

The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

This review provides details on the phytochemicals in green coffee beans and the changes
that occur during roasting. Key compounds in the coffee beverage, produced from the …

The causes of Parkinson's disease (PD), the second most common neurodegenerative
disorder, are still largely unknown. Current thinking is that major gene mutations cause only …

Parkinson's disease is a common progressive bradykinetic disorder that can be accurately
diagnosed. It is characterised by the presence of severe pars-compacta nigral-cell loss, and …

Coffee is the leading worldwide beverage after water and its trade exceeds US $10 billion
worldwide. Controversies regarding its benefits and risks still exist as reliable evidence is …

OBJECTIVE: Coffee is a beverage used worldwide. It includes a wide array of components
that can have potential implication on health. We have reviewed publications on the impact …