Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality
worldwide. Effective prevention and management strategies are essential to reduce the …

The human heart lacks significant regenerative capacity; thus, the solution to heart failure
(HF) remains organ donation, requiring surgery and immunosuppression. The demand for …

Human induced pluripotent stem cell (hiPSC)‐derived cardiac organoids (COs) have shown
great potential in modelling human heart development and cardiovascular diseases, a …

Throughout our lifetime, each beat of the heart requires the coordinated action of multiple
cardiac cell types. Understanding cardiac cell biology, its intricate microenvironments, and …

Organoids-on-chips is an emerging innovative integration of stem cell-derived organoids
with advanced organ-on-chip technology, providing a novel platform for the in vitro …

Organoids, exhibiting the capability to undergo differentiation in specific in vitro growth
environments, have garnered significant attention in recent years due to their capacity to …

Human iPSC-derived cardiac organoids (hiPSC-COs) for cardiotoxicity drug testing via the
variety of cell lines and unestablished protocols may lead to differences in response results …

Cellular membranes play a key role in cell communication with the extracellular environment
and neighboring cells. Any changes, including their composition, packing, physicochemical …

Cardiotoxicity is a prominent cause of drug withdrawal, impacting drug development during
preclinical and clinical phases, as well as post-market approval. Traditional 2-dimensional …

Nowadays 9 of every 10 women take at least one medicine during their pregnancy.
However, unfortunately, many pregnant women have to face a severe problem that there is …