Evolution of the large nucleocytoplasmic DNA viruses of eukaryotes and convergent origins of viral gigantism

EV Koonin, N Yutin - Advances in Virus Research, 2019 - Elsevier
Abstract The Nucleocytoplasmic Large DNA Viruses (NCLDV) of eukaryotes (proposed
order “Megavirales”) comprise an expansive group of eukaryotic viruses that consists of the …

Adenovirus core proteins: structure and function

S Kulanayake, SK Tikoo - Viruses, 2021 - mdpi.com
Adenoviruses have served as a model for investigating viral-cell interactions and
discovering different cellular processes, such as RNA splicing and DNA replication. In …

Mechanisms of DNA packaging by large double-stranded DNA viruses

VB Rao, M Feiss - Annual review of virology, 2015 - annualreviews.org
Translocation of viral double-stranded DNA (dsDNA) into the icosahedral prohead shell is
catalyzed by TerL, a motor protein that has ATPase, endonuclease, and translocase …

Components of adenovirus genome packaging

YS Ahi, SK Mittal - Frontiers in microbiology, 2016 - frontiersin.org
Adenoviruses (AdVs) are icosahedral viruses with double-stranded DNA (dsDNA) genomes.
Genome packaging in AdV is thought to be similar to that seen in dsDNA containing …

Architecture of the baculovirus nucleocapsid revealed by cryo-EM

X Jia, Y Gao, Y Huang, L Sun, S Li, H Li… - Nature …, 2023 - nature.com
Baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been
widely used as a bioinsecticide and a protein expression vector. Despite their importance …

[PDF][PDF] Recent advances in coarse-grained modeling of virus assembly

MF Hagan, R Zandi - Current opinion in virology, 2016 - Elsevier
In many virus families, tens to thousands of proteins assemble spontaneously into a capsid
(protein shell) while packaging the genomic nucleic acid. This review summarizes recent …

Virus-inspired function in engineered protein cages

TGW Edwardson, D Hilvert - Journal of the American Chemical …, 2019 - ACS Publications
The structural and functional diversity of proteins combined with their genetic
programmability has made them indispensable modern materials. Well-defined, hollow …

Genomic and ecological attributes of marine bacteriophages encoding bacterial virulence genes

CB Silveira, FH Coutinho, GS Cavalcanti, S Benler… - BMC genomics, 2020 - Springer
Background Bacteriophages encode genes that modify bacterial functions during infection.
The acquisition of phage-encoded virulence genes is a major mechanism for the rise of …

The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

A Villalta, A Schmitt, LF Estrozi, ERJ Quemin… - Elife, 2022 - elifesciences.org
Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known
about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling …

Role of the DNA-binding protein pA104R in ASFV genome packaging and as a novel target for vaccine and drug development

AC Urbano, F Ferreira - Vaccines, 2020 - mdpi.com
The recent incursions of African swine fever (ASF), a severe, highly contagious,
transboundary viral disease that affects members of the Suidae family, in Europe and China …