Neonicotinoid insecticides: molecular targets, resistance, and toxicity

K Matsuda, M Ihara, DB Sattelle - Annual review of …, 2020 - annualreviews.org
Neonicotinoids have been used to protect crops and animals from insect pests since the
1990s, but there are concerns regarding their adverse effects on nontarget organisms …

[HTML][HTML] Nicotinic acetylcholine receptors: Therapeutic targets for novel ligands to treat pain and inflammation

AJ Hone, JM McIntosh - Pharmacological research, 2023 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) have been historically defined as ligand-gated
ion channels and function as such in the central and peripheral nervous systems. Recently …

Neuronal and extraneuronal nicotinic acetylcholine receptors

M Zoli, S Pucci, A Vilella, C Gotti - Current neuropharmacology, 2018 - ingentaconnect.com
Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …

Neuronal nicotinic receptors: from structure to pathology

C Gotti, F Clementi - Progress in neurobiology, 2004 - Elsevier
Neuronal nicotinic receptors (NAChRs) form a heterogeneous family of ion channels that are
differently expressed in many regions of the central nervous system (CNS) and peripheral …

Structural and functional diversity of native brain neuronal nicotinic receptors

C Gotti, F Clementi, A Fornari, A Gaimarri… - Biochemical …, 2009 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion
channels present in the central and peripheral nervous systems, that are permeable to mono …

Diversity of vertebrate nicotinic acetylcholine receptors

NS Millar, C Gotti - Neuropharmacology, 2009 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) are pentameric neurotransmitter receptors. They
are members of the Cys-loop family of ligand-gated ion channels which also include …

Desensitization of neuronal nicotinic receptors

MW Quick, RAJ Lester - Journal of neurobiology, 2002 - Wiley Online Library
The loss of functional response upon continuous or repeated exposure to agonist,
desensitization, is an intriguing phenomenon if not as yet a well‐defined physiological …

[HTML][HTML] Adrenergic and cholinergic control in the biology of epidermis: physiological and clinical significance

SA Grando, MR Pittelkow, KU Schallreuter - Journal of Investigative …, 2006 - Elsevier
The presence of an autocrine adrenergic and cholinergic intra/intercellular signal
transduction network in the human epidermis contributes significantly to homeostatic and …

Nicotinic acetylcholine receptors in neuropathic and inflammatory pain

AJ Hone, JM McIntosh - FEBS letters, 2018 - Wiley Online Library
Nicotinic acetylcholine receptors (nAChRs) are actively being investigated as therapeutic
targets for the treatment of pain and inflammation, but despite more than 30 years of …

Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors

M Vincler, S Wittenauer, R Parker… - Proceedings of the …, 2006 - National Acad Sciences
α9α10 nicotinic acetylcholine receptors (nAChRs) have been identified in a variety of tissues
including lymphocytes and dorsal root ganglia; except in the case of the auditory system, the …