Advanced paternal age is associated with an increased risk of fathering children with
genetic disorders and other adverse reproductive consequences. However, the mechanisms …

Cortical development consists of a series of synchronised events, including fate transition of
cortical progenitors, neuronal migration, specification and connectivity. It is becoming clear …

Mounting evidence is showing that altered signaling through the nuclear hormone receptor
superfamily can cause abnormal, long-term epigenetic changes which translate into …

Animal studies have shown that exposure to cigarette smoke during pregnancy can induce
neurobehavioral anomalies in multiple subsequent generations. However, little work has …

Neurodevelopmental disorders are on the rise worldwide, with diagnoses that detect
derailment from typical milestones by 3 to 4.5 years of age. By then, the circuitry in the brain …

BACKGROUND Autism spectrum disorder (ASD) is a neurodevelopmental condition
characterized by deficits in social communication and repetitive behaviors. Metabolomic …

Autism spectrum disorders (ASDs) are described as generalized developmental disorders,
with an average age of onset of 36 months. Genetic and environmental factors may …

Cultural and generational trends have increasingly favored “anti‐inflammatory” action,
innovating a new class of analgesic, non‐steroidal anti‐inflammatory drugs (NSAIDs) in the …

Genetic mutations identified in genome-wide association studies can only explain a small
percentage of the cases of complex, highly heritable human conditions, including …

Background. Prenatal nutrition may be an aetiological factor in the development of offspring
autism. However, findings are inconsistent, possibly because of methodological limitations …