Obesity, adipose tissue and vascular dysfunction
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …
are strongly associated with comorbidities such as hypertension and insulin resistance …
Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …
Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria
FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …
two of the major risk factors for these diseases, aging and obesity, are also global problems …
Inflammation of brown/beige adipose tissues in obesity and metabolic disease
F Villarroya, R Cereijo… - Journal of internal …, 2018 - Wiley Online Library
Many of the comorbidities of obesity, including type 2 diabetes and cardiovascular diseases,
are related to the low‐grade chronic inflammation of white adipose tissue. Under white …
are related to the low‐grade chronic inflammation of white adipose tissue. Under white …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials
Sarcopenia, the age-related loss of muscle mass and function, imposes a dramatic burden
on individuals and society. The development of preventive and therapeutic strategies …
on individuals and society. The development of preventive and therapeutic strategies …
Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations
TP Fitzgibbons, MP Czech - Journal of the American Heart …, 2014 - Am Heart Assoc
It is well established that the cardiovascular (CV) risk of obesity is more strongly associated
with visceral rather than subcutaneous adiposity. 1–3 Anthropometric variables that account …
with visceral rather than subcutaneous adiposity. 1–3 Anthropometric variables that account …
Obesity phenotypes and cardiovascular risk: from pathophysiology to clinical management
Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …
The role of perivascular adipose tissue in obesity‐induced vascular dysfunction
N Xia, H Li - British journal of pharmacology, 2017 - Wiley Online Library
Under physiological conditions, perivascular adipose tissue (PVAT) attenuates agonist‐
induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide …
induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide …
Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword
XY Qi, SL Qu, WH Xiong, O Rom, L Chang… - Cardiovascular …, 2018 - Springer
Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the
vasculature, has emerged as an active component of the blood vessel wall regulating …
vasculature, has emerged as an active component of the blood vessel wall regulating …