Advances in Understanding Biomarkers and Treating Neurological Diseases-Role of the Cerebellar Dysfunction and Emerging Therapies

AM Sivalingam - Ageing Research Reviews, 2024 - Elsevier
Cerebellar dysfunction is increasingly recognized as a critical factor in various neurological
diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic …

Tbx1 haploinsufficiency causes brain metabolic and behavioral anomalies in adult mice which are corrected by vitamin B12 treatment

M Caterino, D Paris, G Torromino, M Costanzo, G Flore… - bioRxiv, 2024 - biorxiv.org
Introduction The brain-related phenotypes observed in 22q11. 2 deletion syndrome (22q11.
2DS) are highly variable and their origin is poorly understood. Changes in brain metabolism …

MICROBIOME-MODIFIED METABOLITES PREDICT ACUTE BRAIN INJURY OUTCOME

O DeLeon, HD Ceccato, AM Sidebottom, N Babtain… - bioRxiv, 2024 - biorxiv.org
BACKGROUND. Acute brain injury (ABI)-mediated disruption of the microbiome may
potentiate inflammation and secondary brain injury (SBI). However, microbial-specific …