Transthyretin amyloidosis is a fatal disorder that is characterized primarily by progressive
neuropathy and cardiomyopathy. It occurs in both a mutant form (with autosomal dominant …

Cardiac amyloidosis is characterized by extracellular protein fibril deposition in the
myocardium leading to restrictive heart failure. Both atrial and ventricular arrhythmias, along …

Elevated pro-inflammatory biomarkers and cytokines are associated with morbidity and
mortality in heart failure (HF). Preclinical and clinical studies have shown multiple …

Background: Although atrial fibrillation (AF) is a known complication of amyloidotic
cardiomyopathy (AC), a precise pathophysiological and prognostic characterization is not …

Amyloidosis caused by systemic deposition of transthyretin (TTR) is called ATTR
amyloidosis and mainly includes hereditary ATTR (ATTRv) amyloidosis and wild-type ATTR …

Amyloidosis is an infiltrative disease characterized by deposition of amyloid fibrils within the
extracellular tissue of one or multiple organs. Involvement of the heart, cardiac amyloidosis …

Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) are very
common conditions, particularly in the elderly. However, the mechanisms underlying the two …

Restrictive cardiomyopathy (RCM) is the least common among cardiomyopathies. It can be
idiopathic, familial, or secondary to systematic disorders. Marked increase in left and/or right …

Aims This study aimed to characterize invasive haemodynamics during exercise in subjects
with cardiac amyloidosis (CA). Methods and results The study population numbered 44 …

Cardiac involvement from amyloidosis is of growing interest in the overall literature. Despite
cardiac amyloidosis (CA) has been considered for a long time a rare disease, the diagnostic …