Aortic regurgitation (AR) has an estimated prevalence of 4.9% in the Framingham study, with
moderate or severe AR occurring in 0.5% of the study population. The incidence and …

Abstract Purpose of Review Given that the life expectancy and the burden of hypertension
are projected to increase over the next decade, hypertensive heart disease (HHD) may be …

Aims Cumulative blood pressure (BP) is a measure that incorporates the severity and
duration of BP exposure. The prognostic significance of cumulative BP in young adults for …

Aims Left ventricular (LV) ejection fraction (LVEF) is an extensively utilized marker of LV
function that is often interpreted without recourse to alterations in LV geometry and …

Importance Long-term blood pressure (BP) variability has emerged as a reproducible
measure that is associated with heart failure independent of systemic BP. Visit-to-visit BP …

Aims To evaluate the association of cumulative blood pressure (BP) from young adulthood
to middle age with left atrial (LA) structure/function as assessed by three-dimensional …

BACKGROUND Aortic root (AR) dimension (ARD) at the Valsalva sinuses has been
associated with incident cardiovascular (CV) events in population-based studies, but this …

Background Determinants of changes of aortic root dimension over time are not well
defined. Design We investigated whether specific phenotype and treatment exist predicting …

Background It is unclear whether thoracic aortic volume (TAV) is useful for cardiovascular
(CV) disease prognosis and risk assessment. Purpose This study evaluated cross‐sectional …

Background The prognostic significance of temporal changes in resting heart rate in young
adults for premature heart failure and cardiovascular disease is unclear. We investigated the …