Molecular signature to predict quality of life and survival with glioblastoma using Multiview omics model

R Nassani, Y Bokhari, BM Alrfaei - Plos one, 2023 - journals.plos.org
Glioblastoma multiforme (GBM) patients show a variety of signs and symptoms that affect
their quality of life (QOL) and self-dependence. Since most existing studies have examined …

Integration of IgA and IgG autoantigens improves performance of biomarker panels for early diagnosis of lung cancer

J Pan, L Yu, Q Wu, X Lin, S Liu, S Hu, C Rosa… - Molecular & Cellular …, 2020 - ASBMB
Lung cancer (LC) remains the leading cause of mortality from malignant tumors worldwide.
In our previous study, we surveyed both IgG and IgM-bound serological biomarkers and …

The synergistic antitumour effect of multi-components from Pulsatilla chinensis saponins in NCI-H460 lung cancer cell line through induction of apoptosis

Z Guan, L Chen, Y Zhou, Y Luo, Y Cui, R Liu… - Pharmaceutical …, 2020 - Taylor & Francis
Abstract Context Pulsatilla chinensis (Bunge) Regel (Ranunculaceae) possess antitumour
effects; however, its antitumour potential has not been extensively investigated. Objective To …

NNAT is a novel mediator of oxidative stress that suppresses ER+ breast cancer

C Plasterer, M Semenikhina, SW Tsaih, MJ Flister… - Molecular …, 2023 - Springer
Background Neuronatin (NNAT) was recently identified as a novel mediator of estrogen
receptor-positive (ER+) breast cancer cell proliferation and migration, which correlated with …

Nucleolar protein 3 promotes proliferation of bladder cancer cells through the PI3K-Akt pathway

L Wu, K Zhu, Y Sun, T Li, J Zhu, H Tong… - World Journal of …, 2024 - Springer
Abstract Nucleolar protein 3 (NOL3), as a markedly increased protein across a range of
tumors, has been well acknowledged that plays an anti-apoptotic role in malignancies, while …

Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers

A Meah, V Vedarethinam, R Bronstein, N Gujarati… - Biosensors, 2023 - mdpi.com
High-multiplex detection of protein biomarkers across tissue regions has been an attractive
spatial biology approach due to significant advantages over traditional …

ARC is a critical protector against inflammatory bowel disease (IBD) and IBD-associated colorectal tumorigenesis

Q Wang, T Zhang, X Chang, DY Lim, K Wang, R Bai… - Cancer research, 2020 - AACR
The key functional molecules involved in inflammatory bowel disease (IBD) and IBD-
induced colorectal tumorigenesis remain unclear. In this study, we found that the apoptosis …

[HTML][HTML] Discovery and construction of prognostic model for clear cell renal cell carcinoma based on single-cell and bulk transcriptome analysis

F Zhang, S Yu, P Wu, L Liu, D Wei… - … Andrology and Urology, 2021 - ncbi.nlm.nih.gov
Background Clear cell renal cell carcinoma (ccRCC) is the most common malignant kidney
tumor in adults. Single-cell transcriptome sequencing can provide accurate gene expression …

A double-edged sword: role of apoptosis repressor with caspase recruitment domain (ARC) in tumorigenesis and ischaemia/reperfusion (I/R) injury

K Liu, D Lan, C Li, S Liu, X Dai, T Song, X Wang… - Apoptosis, 2023 - Springer
Apoptosis repressor with caspase recruitment domain (ARC) acts as a potent and
multifunctional inhibitor of apoptosis, which is mainly expressed in postmitotic cells …

[PDF][PDF] Thermal proteomic profiling for detecting protein targets in whole food fraction

W Sinclair - 2022 - islandscholar.ca
Breast cancer is one of the most serious and widespread malignancies worldwide. In the last
few decades, research surrounding phytochemicals, food based bioactive molecules …