Vascular endothelial growth factor in eye disease

JS Penn, A Madan, RB Caldwell, M Bartoli… - Progress in retinal and …, 2008 - Elsevier
Collectively, angiogenic ocular conditions represent the leading cause of irreversible vision
loss in developed countries. In the US, for example, retinopathy of prematurity, diabetic …

[HTML][HTML] Retinopathy of prematurity: A review of pathophysiology and signaling pathways

M Fevereiro-Martins, C Marques-Neves… - survey of …, 2023 - Elsevier
Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the retina and a leading
cause of visual impairment and childhood blindness worldwide. The disease is …

Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies

JC Rivera, M Holm, D Austeng, TS Morken… - Journal of …, 2017 - Springer
Retinopathy of prematurity (ROP) is an important cause of childhood blindness globally, and
the incidence is rising. The disease is characterized by initial arrested retinal vascularization …

Clinical presentation of preeclampsia and the diagnostic value of proteins and their methylation products as biomarkers in pregnant women with preeclampsia and …

M Portelli, B Baron - Journal of pregnancy, 2018 - Wiley Online Library
Preeclampsia (PE) is a disorder which affects 1‐10% of pregnant women worldwide. It is
characterised by hypertension and proteinuria in the later stages of gestation and can lead …

The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3

M Kunizaki, R Hamamoto, FP Silva, K Yamaguchi… - Cancer research, 2007 - AACR
We previously identified SMYD3 as a histone methyltransferase and showed that its
expression was elevated in colorectal, hepatocellular, and breast carcinomas. In the …

Pazopanib ameliorates rotenone-induced Parkinsonism in rats by suppressing multiple regulated cell death mechanisms

HM Mansour, AF Mohamed, MM Khattab… - Food and Chemical …, 2023 - Elsevier
Parkinson's disease (PD) is characterized by motor impairments and progressive
dopaminergic neuronal death in the substantia nigra (SN). Recently, the involvement of …

Medicinal Properties and Active Constituents of Dracocephalum kotschyi and Its Significance in Iran: A Systematic Review

P Heydari, M Yavari, P Adibi, G Asghari… - Evidence‐Based …, 2019 - Wiley Online Library
Objectives. Dracocephalum has over 60 species and is found mainly in the temperate
regions of Asia and Europe. One of these species, ie, Dracocephalum kotschyi Boiss, is …

Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo

C Li, Q Xu - Cellular signalling, 2007 - Elsevier
Increasing evidence has been demonstrated that hypertension-initiated abnormal
biomechanical stress is strongly associated with cardio-/cerebrovascular diseases eg …

Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo [3, 2-d] pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase …

Y Oguro, N Miyamoto, K Okada, T Takagi… - Bioorganic & medicinal …, 2010 - Elsevier
We synthesized a series of pyrrolo [3, 2-d] pyrimidine derivatives and evaluated their
application as type-II inhibitors of vascular endothelial growth factor receptor 2 (VEGFR2) …

The Role of VEGF receptors as molecular target in nuclear medicine for cancer diagnosis and combination therapy

K Masłowska, PK Halik, D Tymecka, A Misicka… - Cancers, 2021 - mdpi.com
Simple Summary The rapid development of diagnostic and therapeutic methods of the
cancer treatment causes that these diseases are becoming better known and the fight …