Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the
establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly …

The treatment of most cancers is still inadequate, despite tremendous steady progress in
drug discovery and effective prevention. Nature is an attractive source of new therapeutics …

Abstract Background Methanolic extracts of Gracilaria tenuistipitata (MEGT) were obtained
from the edible red algae. Previously, we found that water extract of G. tenuistipitata was …

Withaferin A (WFA) is one of the most active steroidal lactones with reactive oxygen species
(ROS) modulating effects against several types of cancer. ROS regulation involves selective …

Background Most chemotherapeutic drugs for killing cancer cells are highly cytotoxic in
normal cells, which limits their clinical applications. Therefore, a continuing challenge is …

The water extract of Gracilaria tenuistipitata have been found to be protective against
oxidative stress-induced cellular DNA damage, but the biological function of the ethanolic …

Lung cancer is a prevalent disease and is one of the leading causes of mortality worldwide.
Despite the development of various anticancer drugs, the prognosis of lung cancer is …

The characteristics of phthalates had been thought to be similar to endocrine disruptors,
which increases cancer risk. The role of phthalates in acquired drug resistance remains …

Withaferin A (WFA) has been reported to inhibit cancer cell proliferation based on high
cytotoxic concentrations. However, the low cytotoxic effect of WFA in regulating cancer cell …

Plasticizers/phthalates play a facilitating role in the development of cancer and help the
tumor to grow and metastasize. Camptothecin (CPT) and its derivatives are known to have …