The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

There are at least two types of cannabinoid receptors (CB1 and CB2). Ligands activating
these G protein-coupled receptors (GPCRs) include the phytocannabinoid Δ9 …

Cannabis sativa has been used for recreational, therapeutic and other uses for thousands of
years. The plant contains more than 120 C 21 terpenophenolic constituents named …

Cannabinoids have numerous physiological effects. In the years since the molecular
identification of the G protein‐coupled receptors CB1 and CB2, the ion channel TRPV1, and …

Endocannabinoids are endogenous ligands of the cannabinoid receptors CB 1 and CB 2.
Two arachidonic acid derivatives, arachidonoylethanolamide (anandamide) and 2 …

Cannabinoids, endocannabinoids and marijuana activate two well‐characterized
cannabinoid receptors (CB‐Rs), CB1‐Rs and CB2‐Rs. The expression of CB1‐Rs in the …

Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …

A meta‐analysis, unlike a literature review, synthesizes previous studies into new results.
Pooled data from 211 studies measured ligand binding affinities at human (Hs) or rat (Rn) …

Plants of the Cannabis genus are the only prolific producers of phytocannabinoids,
compounds that strongly interact with the evolutionarily ancient endocannabinoid receptors …

Endogenous cannabinoids (endocannabinoids) are small molecules biosynthesized from
membrane glycerophospholipid. Anandamide (AEA) is an endogenous intestinal …