Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

Parkinson's disease (PD) is the second most common degenerative disorder. Although the
disease was described more than 200 years ago, its pathogenetic mechanisms have not yet …

Abstract Background Dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD), which share many clinical, neurochemical, and morphological features, have been …

Background Great heterogeneity exists in survival and the interval between onset of motor
symptoms and dementia symptoms across synucleinopathies. We aimed to identify genetic …

Objective The objective of this work was to investigate survival, dementia, and genotype‐
phenotype correlations in patients with Parkinson's disease (PD) with and without mutations …

Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder mainly in middle‐elderly population, which represents diverse nonmotor symptoms …

Lysosomes have fundamental physiological roles and have previously been implicated in
Parkinson's disease,,,–. However, how extracellular growth factors communicate with …

Less than a quarter century after the discovery of SNCA as the first attributable gene in
Parkinson's disease (PD), our knowledge of the genetic architecture underlying this disease …

Importance Parkinson disease (PD) is heterogeneous in symptom manifestation and rate of
progression. Identifying factors that influence disease progression could provide …